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:: Volume 20, Issue 3 (jrds 2023) ::
J Res Dent Sci 2023, 20(3): 139-145 Back to browse issues page
Comparative study of tissue-eosinophils frequency in common oral reactive lesions
Saeedeh Khalesi , Sayed Mohammad Razavi * , Mahta Sadat Taheri
Abstract:   (543 Views)
Background and AimSoft tissue reactive lesions are the most common oral lesions. Eosinophils are leukocytes with multiple functions, which are considered to have multiple roles including angiogenesis and fibrogenesis. Considering the importance of reactive lesions and their prevalence in the Iranian population, this study attempts to investigate the role of eosinophils in the formation of common reactive lesions of the oral cavity.
Material and Methods: In this cross-sectional descriptive-analytical study, 26 case of pyogenic granuloma, 27 case of irritation fibroma and 27 case of peripheral ossifying fibroma were selected from the archive of the Oral Pathology Department of Isfahan Dental School, which were prepared by excisional biopsy method. Clinical information including age, gender and location of the lesion was extracted. Congo red staining was performed and the number of eosinophil was counted. All data was entered into SPSS24 software and was statistically analyzed by Chi-square, Fisher's exact and Mann-Whitney tests. P<0.05 was considered as a significant difference.
Result: The highest mean number of eosinophils was counted in pyogenic granuloma (24.88±32.08) and the lowest was counted in irritiation fibroma (10.11±23.22). According to the Kruskal-Wallis test, there was a significant difference in the average number of eosinophils (P = 0.001)
Conclusion: The number of eosinophils in the studied lesions, especially pyogenic granuloma is noticeable and can play a role in the pathogenesis of these lesions.
Article number: 8
Keywords: Eosinophil,   Oral cavity, Congored pyogenic granuloma
Full-Text [PDF 865 kb]   (371 Downloads)    
Type of Study: original article | Subject: oral patho
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Khalesi S, Razavi S M, Taheri M S. Comparative study of tissue-eosinophils frequency in common oral reactive lesions. J Res Dent Sci 2023; 20 (3) : 8
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Volume 20, Issue 3 (jrds 2023) Back to browse issues page
مجله تحقیق در علوم دندانپزشکی Res Dent Sci
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