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:: Volume 14, Issue 2 (J Res Dent Sci 2017) ::
J Res Dent Sci 2017, 14(2): 109-117 Back to browse issues page
Clinical effects of chlorhexidine gel in the treatment of chronic periodontitis
F Taleghani Dr, R Sadeghi Dr *, N Valaei Eng, R Nejadi Dr, AM Nematollah Dr
, sadeghi@shahed.ac.ir
Abstract:   (3976 Views)

Background and Aim

Local antibacterial agents containing chlorhexidine (CHX) are used as an adjunct to conventional treatment in periodontal patients. In this study, a sustained release, xanthan- based CHX gel was used for non surgical treatment in moderate to advanced periodontitis.

Methods and Materials

In this randomized controlled split-mouth clinical trial, 40 periodontal pockets with probing pocket depth > 5 mm were selected and randomly assigned to the case and control groups. Scaling and root planing (SRP) were performed thoroughly at all sites. Then, chlorhexidine gel and placebo gel were applied subgingivally in test and control sites, respectively. The gels’ application was done two times with one week interval. The clinical parameters including plaque index (PI), papillary bleeding index (PBI), pocket depth (PD) and clinical attachment level (CAL) were evaluated at baseline, after 1 and 3 months. Data analysis was performed using U Mann-Whitney and Friedman tests. 


Statistically significant improvements were observed in PBI, CAL and PD parameters following treatment in each group after 1 and 3 months. Comparison between the two treatment groups showed no significant differences in clinical parameters at any time point.


According to the findings of this study, adjunctive subgingival application of chlorhexidine gel did not improve clinical parameters significantly compared to scaling and root planing treatment in moderate-to-severe chronic periodontitis.

Key words

Locally delivered drugs, Chronic periodontitis, Chlorhexidine,Treatment Outcome

Keywords: Locally delivered drugs, Chronic periodontitis, Chlorhexidine, Treatment Outcome
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Taleghani F, Sadeghi R, Valaei N, Nejadi R, Nematollah A. Clinical effects of chlorhexidine gel in the treatment of chronic periodontitis. J Res Dent Sci. 2017; 14 (2) :109-117
URL: http://jrds.ir/article-1-820-en.html

Volume 14, Issue 2 (J Res Dent Sci 2017) Back to browse issues page
مجله تحقیق در علوم دندانپزشکی Res Dent Sci
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