Abstract:

  Background and Aim: Topical NSAIDs have been shown to be effective in treatment of recurrent aphtous stomititis. Therefore, the purpose of the study was to compare the effect of Triamecinolone asetonide and diclofenac in patients with recurrent aphtous stomititis referred to Shahed dental school in 2011.

  Materials and Methods: In this clinical trial Study 25 patients were divided in two groups (12 persons in control-triamcilonone group and 13 persons in case- diclofenac group). All patients were asked to apply the drug 3 times daily and the effect of therapy was assessed in 0, 2 and 6 days after start of the therapy. Pain level, disease period and ulcer size were compared with in each group and also between case and control groups. 

  Results: Patients in both groups were matched according to the personal and disease specifications. Pain level in day 6 in diclofenac group was 1/6±2/6 and in triamcinolone group was 1/5±2/8 (p<0/9). Ulcer size and treatment results were similar in both groups (p<0/7).

  Conclusion: It seems that both drugs have similar effects. However, considering the corticosteroid side effects, we recommend topical diclofenac therapy in patients with recurrent aphtous stomititis. Moreover, additional research is suggested to compare the effectiveness of the two drug.