Background and Aim: Color stability is an important property of denture base acrylic resin. Color changes indicate aging or damaged dental materials. The purpose of this study was to determine the influence of 3 different types of denture cleansers on the color stability of acrylic resin. 

  Materials and Methods: This experimental study was performed on 40 samples fo 10×55 mm acrylic resins including 10 samples in the control group (BAYER) and 30 samples in the case group. Each group was then divided into 2 categories of smooth and coarse samples. Three cleanser solutions were then prepared as follows: 1. A 200 ml plate of 5.25% sodium hypochloride, 2. A 200 ml plate of varda + vinegar and 3. A 200 ml plate of water with a cleaner tablet named Corega. A spectrophotometer was used to record the initial and final color of each sample before and after placement in the cleaner solutions. Statistical data analysis was done using non parametric Kruskal- Wasliss AND Mann-Whitney Test.

  Results: The difference between 5.25% sodium Hypochloride and other cleansers in terms of color changes was statistically significant ( p<0.001). The Corega tablet solution demonstrated a greater effect on color changes of coarse surfaced acrylic resins compared to smooth surfaced resins.

  Conclusion: Use of 5.25% sodium hypoclorite cleaner will lead to a higher degree of color change in acrylic resins. In addition, the cleaners demonstrate a greater effect on coarse surfaces compared to smooth ones.