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Investigating the effectiveness of glutathione in preventing silver diamine fluoride -induced tooth discoloration in primary teeth: An in vitro study
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Maryam Hajiahmadi    , Mohammadjavad Tarrahi , سمیرا صدیق بطحا * |
| Dental Students’ Research Committee, Department of Pediatric Dentistry, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Isfahan Province, Iran. , samirasadighbatha@gmail.com |
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Abstract: (17 Views) |
Background and aim: Silver diamine fluoride (SDF) is an efficient cariostatic agent with the main disadvantage of tooth staining. This study aimed to evaluate the efficacy of glutathione (GSH) in reducinng SDF-induced tooth discoloration in primary teeth.
Materials and methods: This in-vitro study was performed on 18 extracted primary canines with dentinal caries. Samples were randomly allocated into two treatment groups: SDF 38% (n=9) and SDF 38% mixed with GSH 20% (n=9). Color measurements were performed at four time points: baseline and days 1, 14, and 30 post-treatment using a spectrophotometer and the CIE L*a*b* system, and color changes (ΔE) were reported. Shapiro–Wilk and Independent T tests were used for statistical analysis.
Results: The mean color change (ΔE) values were significantly higher in group1 (SDF) than in group2 (SDF + GSH) at all time points (p <0.001).
Conclusion: The use of glutathione can effectively reduce SDF-induced tooth discoloration in primary teeth and may be used as an adjunctive agent to improve the esthetic outcomes of SDF treatment.
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| Keywords: Glutathione, Potassium iodide, Cariostatic Agents, Silver Compounds, Dental Caries, Tooth Discoloration, Pediatric Dentistry |
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Full-Text [PDF 785 kb]
(13 Downloads)
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Type of Study: original article |
Subject:
Pediatrics
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