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:: Volume 19, Issue 4 (jrds 2022) ::
J Res Dent Sci 2022, 19(4): 289-294 Back to browse issues page
Comparison of the Effect of Ibuprofen and Curcumin on Pain Control after Mandibular Third molar surgery
Seyed Amir Ahadi , Fatemeh Alanchari , Vahid Mesgar zadeh , Maryam Sohrabi
Department of Oral and Maxillofacial Surgery, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran , vahid_mesgar@yahoo.com
Abstract:   (245 Views)
Background and Aim: The aim of this study was to evaluate and compare the effect of curcumin and ibuprofen on pain control, in terms of pain intensity and duration of analgesia after extraction of the third molar of the mandible in the maxillofacial surgery department of the University School of Dentistry Islamic Azad Medical Sciences in the academic year 1400-1399.
Material and Methods: The study was performed as a double-blind randomized clinical trial on 48 patients who were candidates for mandibular third molar surgery. they should also write their pain intensity one hour after taking the second dose of the drug after seeing the first symptoms of pain based on the VAS scale and the duration of their analgesia from the time of taking the drug (which was one hour before surgery for all patients) to the first signs of pain appeared on a piece of paper. Data analysis was performed using Two sample T test power analysis of PASS software version 22.
Results: The results of our study showed that the duration of analgesia after Curcumin use is shorter compared to Ibuprofen (P<0.001). This difference was also statistically significant. Also, after taking the second dose of the drug, patients treated with ibuprofen reported less pain intensity, although this difference was not statistically significant (P=0.39)
Conclusion:  Ibuprofen compared to Curcumin further reduces patients' pain and also has a longer duration of pain for patients after extraction of the third molar of the mandible.
Keywords: Curcumin, Ibuprofen, Tooth Extraction, pain intensity
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Type of Study: original article | Subject: oral surgery
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Ethics code: IR.IAU.DENTAL.REC.1399.081
Clinical trials code: IRCT20210223050469N1←IRCT

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Ahadi S A, Alanchari F, Mesgar zadeh V, Sohrabi M. Comparison of the Effect of Ibuprofen and Curcumin on Pain Control after Mandibular Third molar surgery. J Res Dent Sci 2022; 19 (4) :289-294
URL: http://jrds.ir/article-1-1326-en.html

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Volume 19, Issue 4 (jrds 2022) Back to browse issues page
مجله تحقیق در علوم دندانپزشکی Res Dent Sci
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