Abstract
Background and Aim: the beneficial effects of many herbal mouthrinses on the recovery of periodontal disease have been proven to complement conventional periodontal treatment.. The aim of this study was to compare the effect of pomegranate mouthrinse and chlorhexidine mouthrinse on the treatment of severe chronic periodontitis.
Materials and Methods: This study was a randomized double-blind clinical trial conducted in 2020  at Zahedan University of Medical Sciences on 48 patients with severe chronic periodontitis. For patients in 4 groups, pomegranate peel, pomegranate seed, chlorhexidine mouthrinses and placebo were prescribed. Depth of probe,Modified gingival index (MGI) and bleeding index (BI) were determined and recorded before scaling and 2 weeks and 1 and 3 months after scaling. Data were analyzed using ANOVA and T-pair  statistical tests.
Results: : There was no significant difference between the groups in all the studied parameters before scaling and second week after that(P> 0.05).Depth of probe decreased significantly in the first and third months after scaling in pomegranate and chlorhexidine mouthwashes than in placebo(P <0.05). Inflammatory parameters in the first month after scaling in the chlorhexidine group were significantly lower than in placebo (P <0.05).Also, no significant difference was observed between groups in inflammatory parameters 3 months after scaling(P> 0.05).
Conclusion: According to the results of this study, pomegranate mouthwash can be a good and uncomplicated alternative In patients with periodontitis as a complementary treatment for scaling ,instead of chlorhexidine mouthrinse,.