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:: Volume 11, Issue 3 (J Res Dent Sci 2014) ::
J Res Dent Sci 2014, 11(3): 123-129 Back to browse issues page
Comparison of the Effect of Doxycycline and Licorice on Chronic Periodontitis – A Clinical Trial Study
T Mahmudpourmoteshakker, E Rafiee, SHZ Farhad, A Aminzadeh
Assistant Professor of Microbiology, Dept .of Basic Medical Sciences, Isfahan Azad University (Khorasgan Branch), Isfahan, Iran , t.mahmudpour@yahoo.com
Abstract:   (14527 Views)

 

Abstract

 

Background and Aim: Host modulatory therapy (HMT) is a new method that has been used as adjunctive therapy for periodontal diseases. Licorice tablet contains an extract with anti-inflammatory effects. Considering that most patients prefer to take herbal medications. we found it necessary to compare the effects of licorice tablet and doxycycline on chronic periodontitis.

 

 

 

Materials and Methods: In this interventional clinical trial study, 45 patients with mild to moderate chronic periodontitis were selected. Plaque Index (PI), Pocket Depth (PD), Clinical Attachment Loss (CAL) and Bleeding on Probing (BOP) were recorded for all periodontal patients. Then scaling and root planning was done and patients were divided into three groups.

 

In the first group, a 20mg doxycycline capsule was given to each patient daily, the second group was given a 490mg licorice tablet per day and the third group was given a placebo capsule per day. After 6 weeks, all the above-mentioned parameters were recorded again for all patients. Chi-square, paired sample T and one-way ANOVA tests were used for data analysis.

 

 

 

Results: The mean of PD, CAL and BOP after treatment reduced significantly within the three groups (P <0.05). The mean difference of PD, CAL and BOP between the two groups of doxycycline and licorice was not significant (P =0.54, 0.74 and 0.64, respectively).

 

Conclusion: licorice decreases clinical periodontal indices of similar to doxycycline in chronic periodontitis.

 

Keywords: Chronic periodontitis, Doxycycline, Licorice, Clinical Trial
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Type of Study: original article | Subject: oral surgery
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Mahmudpourmoteshakker T, Rafiee E, Farhad S, Aminzadeh A. Comparison of the Effect of Doxycycline and Licorice on Chronic Periodontitis – A Clinical Trial Study. J Res Dent Sci. 2014; 11 (3) :123-129
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Volume 11, Issue 3 (J Res Dent Sci 2014) Back to browse issues page
مجله تحقیق در علوم دندانپزشکی Res Dent Sci
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