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Does Opioid abuse Increase the prevalence of post-operation infection in the Mandibular Fractures?
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Reza Tabrizi   , Hasan Mirmohammad Sadeghi , Shervin Shafiei *  , Ahmad Shokr , Amin Saedi |
| , shervin.shafee@gmail.com |
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Abstract: (176 Views) |
Abstract
Background and Aim: Post-operative infection is one of the most common complications following mandibular fractures. This study aims to assess the prevalence of post-surgical infection between patients with and without opioid abuse.
Materials and Methods: In this prospective cohort study, the prevalence of post-operation infection was documented in patients who had a mandibular fracture and underwent open reduction with rigid fixation (ORIF). In group1, patients with no opioid abuse, and in group 2, patients with opioid abuse were placed. Age, gender, the time between trauma and operation, plaque index, and white blood cell (WBC) counts of the patients were registered. Fisher's exact test was applied to compare the prevalence of infection between groups.
Results: A total of 150 patients were included in the study, 20 of whom had a history of opioid abuse. In the first group, eight (6.2%) out of 130 patients had signs and symptoms of infection after the operation, and in the second group, 11 people (55%) out of 20 patients experienced infection. There was a statistically significant difference between the two groups regarding the prevalence of postoperative infection (p<0.001).
Conclusion: It seems that opioid abuse along with smoking and poor oral hygiene can lead to postoperative infection in patients with mandibular fracture.
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Article number: 4 |
| Keywords: Infections, Mandibular Fractures, Opioid-Related Disorders, Wound Infection, Bone. |
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Full-Text [PDF 594 kb]
(168 Downloads)
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Type of Study: original article |
Subject:
oral surgery
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