Odontogenic myxofibroma or myxoid neurofibroma?: a case report

Tabatabaei, Seyed Hosein; Barzegar, Mohsen; ,; ,

doi:10.61186/jrds.20.3.153

[Home ] [Archive]

[ فارسی ]

Main Menu

Home

Journal Information

Articles archive

For Authors

For Reviewers

Registration

Contact us

Site Facilities

Indexing & Abstracting

(CC-BY 4.0)

Journal of Research in Dental Sciences is licensed under a "Creative Commons Attribution 4.0 International (CC-BY 4.0)"

Search in website

Receive site information

Volume 20, Issue 3 (jrds 2023)

J Res Dent Sci 2023, 20(3): 153-159

Back to browse issues page

Odontogenic myxofibroma or myxoid neurofibroma?: a case report

Seyed Hosein Tabatabaei ^*

, Mohsen Barzegar

Shahid Sadoughi University of Medical Sciences, Yazd , Taba48971@gmail.com

Abstract: (574 Views)

Background and Aim: Odontogenic myxoma is a benign, uncommon odontogenic tumor that includes about 3 to 6% of odontogenic tumors and has an ectomesenchymal origin. It usually occurs in the second to fourth decade of life. Its common site is lower jaw and posterior parts. Treatment of lesion is complete surgical excision of tumor.
Case Report: The patient, a 17-year-old girl, complained of swelling of palate two months ago. In the panoramic radiograph, a single, multilocular, radiolucent lesion with relatively well demarcated borders was observed on left side of maxilla. The lesion had spread from midline to mesial of left second molar. The lesion was removed by osteoctomy. In microscopic examination, the possibility of myxoid neurofibroma was raised due to presence of wavy cells. Neurofibroma diagnosis was rejected by immunohistochemical method and odontogenic myxofibroma was diagnosed.
Conclusion: In clinical and radiographic examination of this tumor, the possibility of a non-odontogenic lesion of nerve origin was raised, and in microscopic examination of excisional sample, due to the observation of wavy cells, the possibility of a myxoid neurofibroma was raised, but the IHC findings were not in favor of it. Therefore, definitive diagnosis requires relationship between clinical and radiographic findings and examination of various microscopic sections, and in case of doubt, IHC should be performed. Since odontogenic myxoma is a locally invasive lesion and has the potential for recurrence, its correct diagnosis is of great importance.

Article number: 10

Keywords: Odontogenic tumors, neurofibroma, maxilla

Full-Text [PDF 467 kb] (281 Downloads)

Type of Study: case report | Subject: oral patho

References

1. M D, G KKG, M K, C GB, A K, A1 B, et al. Odontogenic Myxoma: Presentation of a Case and Literature Review. EAS J Dent Oral Med. 2022;4(1):48-56. [DOI:10.36349/easjdom.2022.v04i01.008]

2. Kumar S, Mehra P, Ahmad Z. Disfiguring Giant Odontogenic Myxoma of Mandible: A Case Report with Brief Review of Literature. Indian J Otolaryngol Head Neck Surg. 2019;71(Suppl 1):55-8. [DOI:10.1007/s12070-016-1010-4] [PMID] [PMCID]

3. Ghazali AB, Arayasantiparb R, Juengsomjit R, Lam-ubol A. Central Odontogenic Myxoma: A Radiographic Analysis. Int. J. Med. 2021;2021:1093412. [DOI:10.1155/2021/1093412] [PMID] [PMCID]

4. Hatami M, Pakfetrat A, Javadian Langroodi A, Delavarian Z, Rahpeyma A, Saghravanian N, et al. Odontogenic Myxofibroma of the Mandible Along With an Unerupted Third Molar Tooth: Report of a Case. J. Mashhad Dent. Sch. 2016;40(1):93-104.

5. Thompson LDR, Koh SS, Lau SK. Sporadic Neurofibroma of the Tongue Unassociated with Neurofibromatosis Type I: A Clinicopathologic Study of Ten Cases. Head and neck pathol. 2020;14(2):374-80. [DOI:10.1007/s12105-019-01041-1] [PMID] [PMCID]

6. Godishala Swamy SR, Naag S, Bahl S, Priyadarshini E. Odontogenic myxoma: A causality dilemma - Report of a nonpareil case and review of literature. Journal of oral and maxillofacial pathology : JOMFP. 2018;22(Suppl 1):S2-s6. [DOI:10.4103/jomfp.JOMFP_120_16] [PMID] [PMCID]

7. Mohsen B, Hamidreza A, Adele P, Gooya K. Maxillary odontogenic myxoma: A case report. JOBCR. 2022;8(3).

8. Ngham H, Elkrimi Z, Bijou W, Oukessou Y, Rouadi S, Abada RL, et al. Odontogenic myxoma of the maxilla: A rare case report and review of the literature.Ann Med Surg (Lond). 2022;77:103575. [DOI:10.1016/j.amsu.2022.103575] [PMID] [PMCID]

9. Dotta JH, Miotto LN. Odontogenic Myxoma: Systematic review and bias analysis. Eur J Clin Invest. 2020;50(4):e13214. [DOI:10.1111/eci.13214] [PMID]

10. Ramesh S, Govindraju P, Pachipalusu B. Odontogenic myxoma of posterior maxilla - A rare case report. Fam. Med. Prim. 2020;9(3):1744-8. [DOI:10.4103/jfmpc.jfmpc_1189_19] [PMID] [PMCID]

11. Marti-Flich L, Schlund M, Nicot R. Central giant cell granuloma of the mandibular condyle: additional case and literature review. J Oral Med Oral Surg. 2022;28(1):9. [DOI:10.1051/mbcb/2021048]

12. Chen P, Liu B, Wei B, Yu S. The clinicopathological features and treatments of odontogenic keratocysts. Am. J. Cancer Res. 2022;12(7):3479-85.

13. Agani Z, Hamiti-Krasniqi V, Recica J, Loxha MP, Kurshumliu F, Rexhepi A. Maxillary unicystic ameloblastoma: a case report. BMC research notes. 2016;9(1):469. [DOI:10.1186/s13104-016-2260-7] [PMID] [PMCID]

14. Boffano P, Gallesio C, Barreca A, Bianchi FA, Garzino-Demo P, Roccia F. Surgical treatment of odontogenic myxoma. J. Craniofac. Surg. 2011;22(3):982-7. [DOI:10.1097/SCS.0b013e3182101400] [PMID]

15. Kharbouch J, Aziz Z, Benzenzoum Z, Hattab MSK, Aboulouidad S, Fawzi S, et al. Maxillary and mandibular odontogenic myxomas: case report. PAMJ. 2022;42:103. [DOI:10.11604/pamj.2022.42.24.34713]

Send email to the article author

Add your comments about this article

‎ 10.61186/jrds.20.3.153

‎ 20.1001.1.20084676.1402.20.3.10.7

Ethics code: IR.SSU.DENTISTRY.REC.1401.087

Mendeley

Zotero

RefWorks

Tabatabaei S H, Barzegar M. Odontogenic myxofibroma or myxoid neurofibroma?: a case report. J Res Dent Sci 2023; 20 (3) : 10
URL: http://jrds.ir/article-1-1423-en.html

Rights and permissions
	This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Volume 20, Issue 3 (jrds 2023)

Back to browse issues page

Persian site map - English site map - Created in 0.06 seconds with 38 queries by YEKTAWEB 4657