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Evaluation of epithelial lining thickness responding to inflammatory infiltration in Radicular cyst , inflammatory dentigerous cysts and odontogenic keratocycts
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Forooz Keshani    , Neda Kargahi * , Niloofar Shokri , Fateme Abedi |
| Oral and maxillofacial pathology Department , kargahi@dnt.mui.ac.ir |
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Abstract: (2283 Views) |
Background and Aims: radicular cyct(RC), dentigerus cyct(DC) and odontogenic keratocyct(OKC) are the most common odontogenic cycts, respectively. Awareness of the clinical and histopathological characteristics of these lesions is very important in dental treatments, that inflammatory cell infiltration can play an important role in DC and OKCthese odontogenic cysts’ clinical presentationspathogenesis.
Materials and Methods: In this descriptive-analytic study, 396 patient’s files (216 RC, 90 inflammatory DC and 90 inflammatory OKC) histopathologicaly were examined by two oral and maxillofacial pathologists simultaneously for evaluation the epithelium thickness, type and degree of inflammatory infiltration. The data were analysed using spss software using Spearman and Mann-Whitney tests.
Results: Histopathologicaly the cyst linings were mainly normal in DC and RC and atrophic in OKC and RC. In all three cycts, sever inflammation were more common. There were a significant relation with epithelial thickness and degree of inflammation in RC (Pvalue=0.004). In RC, mixed inflammation with plasma cell predominance was seen while, chronic inflammation with dominance of lymphocyte were presented in 2 other cysts.
Conclusion: it seems, thickness of epithelium has been atrophic in periapical cyst and inflammatory odontogenic cyct and it would be normal in inflamed Dentigerous cyst. There was a reverse relationship between epithelial thickness and degree of inflammation in periapical cyct. |
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| Keywords: inflammation, dentigerus cyct, odontogenic keratocyct |
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Full-Text [PDF 521 kb]
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Type of Study: original article |
Subject:
oral patho
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