fa بررسی اثر دارونما بر ادراک درد حین انجام جرمگیری و تسطیح سطح ریشه دندان ها جراحی- oral surgery مطالعه اصیل original article <p><font face="Times New Roman" size="3">&nbsp;</font></p> <h5 dir="rtl" style="margin: 0cm 0cm 0pt text-align: justify unicode-bidi: embed direction: rtl"><b><span b="" dir="rtl" fa="" face="Times New Roman" font="" h5="" lang="AR-SA" mso-ascii-font-family:="" mso-bidi-font-family:="" mso-bidi-language:="" mso-hansi-font-family:="" new="" roman="" size="3" span="" style="font-family: " times=""><font size="3">سابقه و هـدف:</font></span></b><b><span b="" dir="ltr" lang="AR-SA" mso-bidi-font-family:="" new="" roman="" style="font-family: " times=""><font size="3">&nbsp;</font></span></b><span .="" 9pt="" b="" font="" font-size:="" lang="AR-SA" mso-ascii-font-family:="" mso-hansi-font-family:="" new="" roman="" size="3" span="" style="font-family: " times="">(</span><span 9pt="" b="" dir="ltr" font-size:="" lang="X-NONE" mso-bidi-font-family:="" new="" roman="" style="font-family: " times="">SRP</span><span 9pt="" b="" font-size:="" lang="AR-SA" mso-ascii-font-family:="" mso-hansi-font-family:="" new="" roman="" span="" style="font-family: " times=""><font size="3"> بعنوان مدل کلینیکی با هدف ارزیابی اثر ضد درد دارونما انجام شد.</font></span></h5> <p><font face="Times New Roman" size="3">&nbsp;</font></p> <h5 dir="rtl" style="margin: 0cm 0cm 0pt text-align: justify unicode-bidi: embed direction: rtl"><b><span b="" lang="AR-SA" style="font-family: "><font size="3">مواد و روش‌ها: </font></span></b><span b="" lang="AR-SA" style="font-family: "><font size="3">دراین کارآزمایی بالینی تصادفی دو سوکور و کنترل شده تعداد 182 بیمار پس از اخذ رضایت نامه ی کتبی و ثبت خصوصیات دموگرافیک، در دو گروه دارونما (مورد) شاهد و تحت درمان </font></span><span b="" dir="ltr" lang="X-NONE" style="font-size: 9pt mso-bidi-font-family: "><font face="Times New Roman">SRP</font></span><span b="" lang="AR-SA" style="font-family: "><font size="3"> قرار گرفتند. تمام شرکت کنندگان پرسش نامه ی اضطراب در دندانپزشکی را تکمیل نمودند. بیماران با استفاده از بلوکهای تصادفی در دو گروه قرار گرفتند. در گروه مورد </font><span style="mso-spacerun: yes"><font face="B Nazanin" size="3">&nbsp;</font></span><font size="3">نیم ساعت قبل از درمان کپسول دارونما را به عنوان داروی ضد درد دریافت کردند و درگروه شاهد، دارویی دریافت نمیشد. میزان درد بلافاصله پس از انجام </font></span><span b="" dir="ltr" lang="X-NONE" style="font-size: 9pt mso-bidi-font-family: "><font face="Times New Roman">SRP</font></span><span b="" lang="X-NONE" style="font-family: "><font size="3">&nbsp;</font></span><span b="" lang="AR-SA" style="font-family: "><font size="3">در هر سکستانت با مقیاس 5 درجه ای لیکرت </font></span><font face="Times New Roman"><span b="" dir="ltr" lang="X-NONE" style="font-size: 9pt mso-bidi-font-family: ">VRS</span><span b="" dir="ltr" lang="X-NONE" style="mso-bidi-font-family: "><font size="3">-5</font></span></font><span b="" lang="AR-SA" style="font-family: "><font size="3"> و نیز به روش </font></span><span b="" dir="ltr" lang="X-NONE" style="font-size: 9pt mso-bidi-font-family: "><font face="Times New Roman">VAS</font></span><span b="" lang="AR-SA" style="font-family: "><font size="3"> اندازه گیری و ثبت گردید. تجزیه و تحلیل داده ها با آزمونهای آماری</font><span style="mso-spacerun: yes"><font face="B Nazanin" size="3">&nbsp;</font></span><font size="3">کای دو و </font></span><span b="" dir="ltr" lang="X-NONE" style="font-size: 9pt mso-bidi-font-family: "><font face="Times New Roman">Mann-U-Whitney</font></span><span b="" lang="AR-SA" style="font-family: "><font size="3"> به کمک نرم افزار آماری </font></span><span b="" dir="ltr" lang="X-NONE" style="font-size: 10pt mso-bidi-font-family: "><font face="Times New Roman">SPSS 19</font></span><span b="" lang="AR-SA" style="font-family: "><font size="3"> انجام گرفت.</font></span></h5> <p><font face="Times New Roman" size="3">&nbsp;</font></p> <h5 dir="rtl" style="margin: 0cm 0cm 0pt text-align: justify unicode-bidi: embed direction: rtl"><b><span b="" lang="AR-SA" style="font-family: "><font size="3">یافته‌ها: </font></span></b><span b="" lang="AR-SA" style="font-family: "><font size="3">گروه مورد و شاهد از نظر سطح اضطراب، سن، جنس، عمق پاکت و سطح چسبندگی کلینیکی مشابه بودند. (0/05</font></span><font face="Times New Roman"><span lang="AR-SA"><font size="3"><</font></span><span dir="ltr" style="mso-ansi-language: EN-US"><font size="3">P</font></span><span lang="FA" style="mso-bidi-language: FA mso-ansi-language: EN-US"><font size="3">)</font></span></font><span b="" lang="AR-SA" style="font-family: "><font size="3"> میزان درد در معیار </font></span><span b="" dir="ltr" lang="X-NONE" style="font-size: 9pt mso-bidi-font-family: "><font face="Times New Roman">VAS</font></span><span b="" lang="AR-SA" style="font-family: "><font size="3"> و </font></span><font face="Times New Roman"><span b="" dir="ltr" lang="X-NONE" style="font-size: 9pt mso-bidi-font-family: ">VRS</span><span b="" dir="ltr" lang="X-NONE" style="mso-bidi-font-family: "><font size="3">-5</font></span></font><span b="" lang="AR-SA" style="font-family: "><font size="3"> بین دو گروه دارونما و شاهد با استفاده از آزمون آماری تک متغیره تفاوت معنی دار آماری را نشان نداد. آنالیز همبستگی اسپیرمن بین دو مقیاس درد </font></span><span b="" dir="ltr" lang="X-NONE" style="font-size: 9pt mso-bidi-font-family: "><font face="Times New Roman">VAS</font></span><span b="" lang="AR-SA" style="font-family: "><font size="3"> و </font></span><font face="Times New Roman"><span b="" dir="ltr" lang="X-NONE" style="font-size: 9pt mso-bidi-font-family: ">VRS</span><span b="" dir="ltr" lang="X-NONE" style="mso-bidi-font-family: "><font size="3">-5</font></span></font><span b="" lang="AR-SA" style="font-family: "><font size="3"> همبستگی معنی داری نشان داد (0/0001></font></span><span b="" dir="ltr" lang="X-NONE" style="mso-bidi-font-family: "><font face="Times New Roman" size="3">P</font></span><span b="" lang="AR-SA" style="font-family: "><font size="3">) </font></span></h5> <p><font face="Times New Roman" size="3">&nbsp;</font></p> <h5 dir="rtl" style="margin: 0cm 0cm 0pt text-align: justify unicode-bidi: embed direction: rtl"><b><span b="" lang="AR-SA" style="font-family: "><font size="3">نتیجه گیری: </font></span></b><span b="" lang="AR-SA" style="font-family: "><font size="3">این مطالعه نشان داد که میزان درد در حین </font></span><span b="" dir="ltr" lang="X-NONE" style="font-size: 9pt mso-bidi-font-family: "><font face="Times New Roman">SRP</font></span><span b="" lang="AR-SA" style="font-family: "><font size="3"> با استفاده از دارونما کاهش نمی یابد. </font></span></h5> <p><font face="Times New Roman" size="3">&nbsp;</font></p> <p><font face="Times New Roman" size="3">&nbsp;</font></p> <p style="margin: 0cm 0cm 0pt text-align: justify line-height: normal mso-pagination: none"><b><span font-size:="" new="" style="font-family: " times="">Abstract: </span></b></p> <p><font face="Times New Roman" size="3">&nbsp;</font></p> <p style="margin: 0cm 0cm 0pt text-align: justify line-height: normal mso-pagination: none"><span font-size:="" new="" style="font-family: " times="">&nbsp;</span></p> <p><font face="Times New Roman" size="3">&nbsp;</font></p> <p style="margin: 0cm 0cm 0pt text-align: justify line-height: 120% vertical-align: middle -ms-text-autospace: mso-layout-grid-align: none"><b><span 10pt="" calibri="" font-size:="" mso-bidi-language:="" mso-fareast-font-family:="" new="" style="color: black line-height: 120% font-family: " times="">Background and Aim:</span></b><span 10pt="" calibri="" font-size:="" mso-bidi-language:="" mso-fareast-font-family:="" new="" style="color: black line-height: 120% font-family: " times=""> Placebo analgesia has not been investigated extensively in dental settings. Using scaling and root planning (SRP) as a model, this investigation aimed at evaluating the placebo analgesia during SRP.</span></p> <p><font face="Times New Roman" size="3">&nbsp;</font></p> <p style="margin: 0cm 0cm 0pt text-align: justify line-height: 120% vertical-align: middle -ms-text-autospace: mso-layout-grid-align: none"><span 10pt="" calibri="" font-size:="" mso-bidi-language:="" mso-fareast-font-family:="" new="" style="color: black line-height: 120% font-family: " times="">&nbsp;</span></p> <p><font face="Times New Roman" size="3">&nbsp;</font></p> <p style="margin: 0cm 0cm 0pt text-align: justify line-height: 120% vertical-align: middle -ms-text-autospace: mso-layout-grid-align: none"><b><span 10pt="" calibri="" font-size:="" mso-bidi-language:="" mso-fareast-font-family:="" new="" style="color: black line-height: 120% font-family: " times="">Materials and Methods: </span></b><span 10pt="" calibri="" font-size:="" mso-bidi-language:="" mso-fareast-font-family:="" new="" style="color: black line-height: 120% font-family: " times="">Patients participated in this double-blind, randomized, controlled clinical trial. Having signed an informed consent form, and obtaining demographic characteristics, all the individuals filled a modified dental anxiety index questionnaire. Based on random blocks, 91 patients were given one placebo capsule 30 minutes before SRP as a potent pain killer, and 91 control subjects received SRP alone. Pain was recorded using a 10 centimeter VAS as well as a 5-point verbal Likert scale (VRS-5) during SRP for each sextant of dentition. Statistical analysis was done by chi-square, Spearman correlation coefficient, and Mann-U-Whitney tests using SPSS software version19.</span></p> <p><font face="Times New Roman" size="3">&nbsp;</font></p> <p style="margin: 0cm 0cm 0pt text-align: justify line-height: 120% vertical-align: middle -ms-text-autospace: mso-layout-grid-align: none"><span 10pt="" calibri="" font-size:="" mso-bidi-language:="" mso-fareast-font-family:="" new="" style="color: black line-height: 120% font-family: " times="">&nbsp;</span></p> <p><font face="Times New Roman" size="3">&nbsp;</font></p> <p style="margin: 0cm 0cm 0pt text-align: justify line-height: 120% vertical-align: middle -ms-text-autospace: mso-layout-grid-align: none"><b><span 10pt="" calibri="" font-size:="" mso-bidi-language:="" mso-fareast-font-family:="" new="" style="color: black line-height: 120% font-family: " times="">Results:</span></b><span 10pt="" calibri="" font-size:="" mso-bidi-language:="" mso-fareast-font-family:="" new="" style="color: black line-height: 120% font-family: " times=""> There was no statistical difference between placebo and control groups regarding anxiety, age, sex, pocket depth, and clinical attachment level (P>0.05).<span style="mso-spacerun: yes"><font face="Times New Roman" size="2">&nbsp;</font></span>VAS and VRS-5 scores were not statistically different between case and control subjects using Mann-Whitney test. Spearman rank test<span style="mso-spacerun: yes"><font face="Times New Roman" size="2">&nbsp;</font></span>revealed a correlation between the two pain measuring methods (P<0.0001).</span></p> <p><font face="Times New Roman" size="3">&nbsp;</font></p> <p style="margin: 0cm 0cm 0pt text-align: justify line-height: 120% vertical-align: middle -ms-text-autospace: mso-layout-grid-align: none"><span 10pt="" calibri="" font-size:="" mso-bidi-language:="" mso-fareast-font-family:="" new="" style="color: black line-height: 120% font-family: " times="">&nbsp;</span></p> <p><font face="Times New Roman" size="3">&nbsp;</font><b><span 10pt="" ar-ye="" calibri="" en-us="" font-size:="" mso-ansi-language:="" mso-bidi-language:="" mso-fareast-font-family:="" mso-fareast-language:="" new="" style="color: black line-height: 115% font-family: " times="">Conclusion:</span></b><span 10pt="" ar-ye="" calibri="" en-us="" font-size:="" mso-ansi-language:="" mso-bidi-language:="" mso-fareast-font-family:="" mso-fareast-language:="" new="" style="color: black line-height: 115% font-family: " times=""> Within the limitations of this study, the placebo medication is not capable of reducing pain during SRP</span></p> اثر دارونما, جرم گیری دندان, درد Placebo, Scaling, Pain 71 77 http://jrds.ir/browse.php?a_code=A-10-791-6&slc_lang=fa&sid=1 G Radafshar گلپر رادافشار golishad@gmail.com 10031947532846009745 10031947532846009745 Yes S Hajizadeh سمانه حاجی زاده 10031947532846009746 10031947532846009746 No E Kazemnezhad Leyli احسان کاظم نژاد لیلی 10031947532846009747 10031947532846009747 No N Mirfarhadi نسترن میر فرهادی 10031947532846009748 10031947532846009748 No