journal of research in dental sciences

fa مقایسه میزان سطح بزاقی و مایع شیار لثه ای آلکالین فسفاتاز دربیماران پریودنتیت سیگاری، غیرسیگاری و افراد سالم The comparison of GCF and Salivary level of ALP in smokers, non-smokers with periodontitis and in healthy subjects مواد دندانی Dental materiall مطالعه اصیل original article   <h5 dir="rtl" style="margin: 0cm 0cm 0pt text-align: justify line-height: 115% unicode-bidi: embed direction: rtl -ms-text-justify: kashida text-kashida: 0%">سابقه و هدف: <span b="" color="#0000ff" dir="ltr" face="Times New Roman" font="" lang="AR-SA" mso-ascii-font-family:="" mso-bidi-font-family:="" mso-hansi-font-family:="" new="" roman="" size="3" span="" style="font-family: " times="">در بزاق و پریودنتیت در مطالعات محدودی مورد مطالعه قرار گرفته است و در هیچ تحقیقی ارتباط میزان غلظت ALP <span .="" b="" color="#0000ff" dir="ltr" face="Times New Roman" font="" lang="AR-SA" mso-ascii-font-family:="" mso-bidi-font-family:="" mso-hansi-font-family:="" new="" roman="" size="3" span="" style="font-family: " times="">مایع شیار لثهای و بزاق در بیماران پریودونتیت سیگاری، غیر سیگاری و افراد سالم بود.</h5>   <h5 dir="rtl" style="margin: 0cm 0cm 0pt text-align: justify unicode-bidi: embed direction: rtl"><span .="" 3="" 5="" 50-35="" 7-5="" 90="" :="" b="" color="#0000ff" dir="ltr" face="Times New Roman" font="" lang="AR-SA" mso-ascii-font-family:="" mso-bidi-font-family:="" mso-hansi-font-family:="" new="" roman="" size="3" span="" style="font-family: " times="">در مایع شیار لثه ای و بزاق در نمونه های جمع آوری شده اندازه گیری شد. ازآزمون های آماری ANOVA <span b="" dir="rtl" face="Times New Roman" font="" h5="" lang="AR-SA" mso-ascii-font-family:="" mso-bidi-font-family:="" mso-hansi-font-family:="" new="" roman="" size="3" span="" style="font-family: " times="">یافته ها: میانگین میزان غلظت ALP <span 0="</span" arial="" b="" dir="ltr" face="Times New Roman" font="" h5="" lang="AR-SA" mso-ascii-font-family:="" mso-bidi-font-family:="" mso-hansi-font-family:="" new="" roman="" size="3" span="" style="font-family: " times="">میانگین میزان غلظت ALP <span 0="</span" arial="" b="" dir="ltr" face="Times New Roman" font="" lang="AR-SA" mso-ascii-font-family:="" mso-bidi-font-family:="" mso-hansi-font-family:="" new="" roman="" size="3" span="" style="font-family: " times="">میانگین میزان غلظت ALP <span arial="" b="" dir="rtl" face="Times New Roman" font="" h5="" lang="AR-SA" mso-ascii-font-family:="" mso-bidi-font-family:="" mso-hansi-font-family:="" new="" roman="" size="3" span="" style="font-family: " times="">نتیجه گیری: نتایج این تحقیق بیانگر آن است که میزان غلظت مایع شیار لثه ای ALP <span b="" color="#0000ff" dir="ltr" face="Times New Roman" font="" lang="AR-SA" mso-ascii-font-family:="" mso-bidi-font-family:="" mso-hansi-font-family:="" new="" roman="" size="3" span="" style="font-family: " times="">مایع شیار لثه ای در بیماران پریودنتیت سیگاری بیشتر از افراد غیر سیگاری است. این امر شاید یکی از دلایلی است که در افراد سیگاری احتمال تخریب استخوان آلوئو لار بیشتر است.</h5>   <h5 dir="rtl" style="margin: 0cm 0cm 0pt text-align: justify unicode-bidi: embed direction: rtl"> </h5>     Abstract:       Background and Aim: Periodontal destruction occurs in an episodic fashion, with periods of exacerbation and quiescence. It is therefore important to diagnose periodontal diseases in active phase. Various diagnostic markers have been identified in GCF and saliva. The aim of this study was to compare the salivary and GCF levels of alkaline phosphatase (ALP) in patients with periodontitis, smokers with periodontitis and healthy subjects.       Materials and Methods:In this descriptive study 90 subjects aged 30-50 without any apparent systemic disease were chosen and divided to 3 equal groups: smokers with periodontitis, non-smokers with periodontitis and healthy subjects. In healthy subjects, GCF samples were collected from gingival sulcus. In patients with periodontitis, GCF was collected from pockets of 5-7 mm of depth. About 5 ml of un-stimulated whole saliva was collected from all subjects. All GCF and salivary samples were sent to the laboratory for ALP measurement. ANOVA and Tukey's tests were used for statistical analysis.       Results: The results of this study showed that the mean level of ALP in saliva and GCF was higher in the first and second groups compared to the third group. The mean level of ALP in GCF was higher in the first group compared to the second group. The mean level of ALP in saliva was not statistically different between the first and second group.       Conclusion: It is possible to use both GCF and salivary levels of ALP as diagnostic markers for periodontitis. Higher levels of ALP in GCF samples of smokers with periodontitis could explain the higher rate of alveolar bone destruction in smokers.   آلکالین فسفاتاز, پریودنتیت, بزاق, مایع شیار لثه ای, استعمال دخانیات Alkaline Phosphatase, Periodontitis, saliva, gingival crevicular fluid, smoking 236 241 http://jrds.ir/browse.php?a_code=A-10-12-1&slc_lang=fa&sid=1 M Ketabi محمد کتابی ketabimohammad@yahoo.com 10031947532846009603 10031947532846009603 Yes M Mesripour منوچهر مصری پور 10031947532846009604 10031947532846009604 No E Rafiei احسان رفیعی 10031947532846009605 10031947532846009605 No