:: Volume 14, Issue 3 (jrds 2017) ::
J Res Dent Sci 2017, 14(3): 151-156 Back to browse issues page
Evaluation of relationship between cigarette smoking and sIgA
Simin Lesan , Farnaz Hajifattahi , Fatemeh Jannatabadi , Taraneh Farrokhnia
, dr_h_fattahi@yahoo.com
Abstract:   (9631 Views)

Background & Aim: sIgA is the prominent immunoglobulin in whole saliva and is considered to be the main specific defense mechanism in the oral cavity. Smoking can alter the level of salivary sIgA. The aim of this study was to investigate the relationship between smoking and sIgA.
Materials & Methods: In this Historical Cohort 40 people which were divided into two groups (20 in smokers group and 20 in control group) were examined.  Data such as age, gender, BOP, Oral lesions, systemic disease, use of medicine, xerostomia, CAL and history of dental treatment in 1 last month were collected and fill out the questionnaire, and clinical examination was done. Then about 1cc of unstimulated saliva was collected by the spitting method from all subjects between 09:00 to12:00 and transferred to the laboratory in the next 2 hours .The Data were analyzed by t-test and Multiple linear regression test.
Results: The results indicated that the salivary secretory IgA concentration was significantly lower in the smoker group (164.23±92.61) than controls (232.48±148.02). (p=0.042).
Conclusion: In this research, smoking was associated with a significant decreased in secretory IgA concentration.
    Key Words: IgA, Smoking, Immune system 

Keywords: IgA, Smoking, Immune system
Full-Text [PDF 264 kb]   (3290 Downloads)    
Type of Study: original article | Subject: Oral Medicine

XML   Persian Abstract   Print

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 14, Issue 3 (jrds 2017) Back to browse issues page