fa مقایسه کلینیکی کاربرد یک سیکل منفرد درمان فوتودینامیک به عنوان مکمل جرم گیری با جرمگیری توسط اولتراسونیک در درمان پریودنتیت جراحی- oral surgery مطالعه اصیل original article <p><font face="Times New Roman" size="3">&nbsp;</font></p> <h4 dir="rtl" style="margin: 12pt 0cm 3pt text-align: justify unicode-bidi: embed direction: rtl -ms-text-justify: kashida text-kashida: 0%"><span b="" lang="FA" mso-bidi-language:="" style="font-family: "><font size="3">خلاصه: </font></span></h4> <p><font face="Times New Roman" size="3">&nbsp;</font></p> <h5 dir="rtl" style="margin: 0cm 0cm 0pt text-align: justify unicode-bidi: embed direction: rtl -ms-text-justify: kashida text-kashida: 0%"><b><span b="" lang="AR-SA" style="font-family: "><font size="3">سابقه و هدف:</font></span></b><span b="" lang="AR-SA" style="font-family: "><font size="3"> هدف اصلی درمان پریودنتال بهبود علایم کلینیکی التهاب می باشد.درمان فوتودینامیک شامل کاربرد منبع نوری و ماده حساس به نور می تواند به عنوان مکمل درمان معمول پریودنتیت موثرباشد.هدف این مطالعه مقایسه کلینیکی کاربرد یک سیکل منفرد از درمان فوتودینامیک به عنوان مکمل درمان جرم گیری با جرم گیری به تنهایی در درمان پریودنتیت مزمن در دوره سه ماهه<span style="mso-spacerun: yes"><font face="B Nazanin">&nbsp;</font></span></font><font size="3">در شهر اصفهان می باشد.</font></span></h5> <p><font face="Times New Roman" size="3">&nbsp;</font></p> <h5 dir="rtl" style="margin: 0cm 0cm 0pt text-align: justify unicode-bidi: embed direction: rtl -ms-text-justify: kashida text-kashida: 0%"><font size="3"><b><span b="" lang="AR-SA" style="font-family: ">مواد و روش‌ها: </span></b><span b="" lang="AR-SA" style="font-family: ">دراین کارآزمایی بالینی مداخله ای بیست بیمار مبتلا به پریودنتیت مزمن خفیف تامتوسط دارای حداقل سه دندان با عمق پاکت بین 6-3 میلیمتر و خونریزی حین پروب کردن انتخاب شدند.</span><span b="" dir="ltr" lang="AR-SA" mso-ansi-language:="" style="mso-bidi-font-family: "><font face="Times New Roman">&nbsp;</font></span><span b="" lang="AR-SA" style="font-family: ">با بهره گیری از روش تقسیم دهان،هر بیمار درمان جرم گیری تنها (گروه شاهد) را دریک کوادرانت ودرمان جرم گیری به همراه فوتودینامیک (گروه مورد) رادر دندانهای کوادرانت دیگر</span><span b="" dir="ltr" lang="AR-SA" mso-ansi-language:="" style="mso-bidi-font-family: "><font face="Times New Roman">&nbsp;</font></span><span b="" lang="AR-SA" style="font-family: ">دریافت نمود.</span><span b="" dir="ltr" lang="AR-SA" mso-ansi-language:="" style="mso-bidi-font-family: "><font face="Times New Roman">&nbsp;</font></span><span b="" lang="AR-SA" style="font-family: ">معیارهای کلینیکی شامل عمق پاکت، ازدست رفتن چسبندگی کلینیکی، خونریزی حین پروب و شاخص خونریزی از پاپیلا در ابتدا و 90 روز پس از درمان اندازه گیری شدند.</span><span b="" dir="ltr" lang="AR-SA" mso-ansi-language:="" style="mso-bidi-font-family: "><font face="Times New Roman">&nbsp;</font></span><span b="" lang="AR-SA" style="font-family: ">درتحلیل نتایج از آزمون های تی- مستقل، تی- زوجی، من- ویتنی و ویلکاکسون استفاده شد.</span></font></h5> <p><font face="Times New Roman" size="3">&nbsp;</font></p> <h5 dir="rtl" style="margin: 0cm 0cm 0pt text-align: justify unicode-bidi: embed direction: rtl -ms-text-justify: kashida text-kashida: 0%"><font size="3"><b><span b="" lang="AR-SA" style="font-family: ">یافته‌ها:</span></b><span b="" lang="AR-SA" style="font-family: ">&nbsp;</span><span b="" en-us="" lang="FA" mso-ansi-language:="" mso-bidi-language:="" style="font-family: ">شاخص های خونریزی به طور معناداری در هرگروه کاهش یافتند و </span><span lang="FA" style="mso-ansi-language: EN-US mso-bidi-language: FA"><span style="mso-spacerun: yes"><font face="Times New Roman">&nbsp;</font></span></span><span b="" en-us="" lang="FA" mso-ansi-language:="" mso-bidi-language:="" style="font-family: ">اختلاف بین دوگروه نیز معنی دار بود. (001/0</span><font face="Times New Roman"><span lang="FA" style="mso-ansi-language: EN-US mso-bidi-language: FA">></span><span dir="ltr" style="mso-ansi-language: EN-US mso-bidi-language: FA">P</span><span lang="FA" style="mso-ansi-language: EN-US mso-bidi-language: FA">) </span></font></font><span b="" en-us="" lang="FA" mso-ansi-language:="" mso-bidi-language:="" style="font-family: "><span style="mso-spacerun: yes"><font face="B Nazanin" size="3">&nbsp;</font></span><font size="3">گرچه اختلاف کاهش عمق پاکت و ازدست رفتن چسبندگی کلینیکی بین دو گروه معنادار نبود (به ترتیب 61/0= </font></span><font size="3"><span b="" dir="ltr" en-us="" mso-ansi-language:="" mso-bidi-language:="" style="mso-bidi-font-family: "><font face="Times New Roman">P</font></span><span b="" en-us="" lang="FA" mso-ansi-language:="" mso-bidi-language:="" style="font-family: "> و 14/0= </span><span b="" dir="ltr" en-us="" mso-ansi-language:="" mso-bidi-language:="" style="mso-bidi-font-family: "><font face="Times New Roman">P</font></span></font><span b="" en-us="" lang="FA" mso-ansi-language:="" mso-bidi-language:="" style="font-family: "><font size="3">) ولی کاهش<span style="mso-spacerun: yes"><font face="B Nazanin">&nbsp;</font></span></font><font size="3">این پارامترها پس ازدرمان در هرگروه معنادار بود. (001/0</font></span><font size="3"><font face="Times New Roman"><span lang="FA" style="mso-ansi-language: EN-US mso-bidi-language: FA">></span><span dir="ltr" style="mso-ansi-language: EN-US mso-bidi-language: FA">P</span><span lang="FA" style="mso-ansi-language: EN-US mso-bidi-language: FA">)</span></font></font></h5> <p><font face="Times New Roman" size="3">&nbsp;</font><b><span 12pt="" ar-sa="" b="" dir="rtl" en-us="" font-size:="" lang="AR-SA" mso-ansi-language:="" mso-ascii-font-family:="" mso-bidi-language:="" mso-fareast-font-family:="" mso-fareast-language:="" mso-hansi-font-family:="" new="" span="" style="font-family: " times="">&nbsp;</span><span lang=&quot;FA&quot; style=&quot;letter-spacing: -0.2pt font-family: &quot; b=&quot;&quot; nazanin&quot;=&quot;&quot; font-size:=&quot;&quot; 12pt=&quot;&quot; mso-fareast-font-family:=&quot;&quot; &quot;times=&quot;&quot; new=&quot;&quot; roman&quot;=&quot;&quot; mso-ansi-language:=&quot;&quot; en-us=&quot;&quot; mso-fareast-language:=&quot;&quot; mso-bidi-language:=&quot;&quot; fa=&quot;&quot; mso-ascii-font-family:=&quot;&quot; mso-hansi-font-family:=&quot;&quot; roman&quot;&quot;=&quot;&quot; dir=&quot;rtl&quot;>کاربرد یک سیکل از درمان فوتودینامیک در کاهش شاخص های خونریزی موثر بود اما اثرات کلینیکی افزون تری درمقایسه با جرمگیری تنها دربرنداشت</b></p> <p><font face="Times New Roman" size="3">&nbsp;</font></p> <p style="margin: 0cm 0cm 0pt text-align: justify line-height: 150% unicode-bidi: embed direction: ltr -ms-text-autospace: -ms-text-justify: kashida text-kashida: 0% mso-layout-grid-align: none"><b><span 12pt="" font-size:="" mso-fareast-font-family:="" new="" style="line-height: 150% font-family: " times="">ABSTRACT</span></b></p> <p><font face="Times New Roman" size="3">&nbsp;</font><b><span 12pt="" calibri="" en-us="" font-size:="" mso-ansi-language:="" mso-bidi-language:="" mso-fareast-font-family:="" mso-fareast-language:="" new="" style="line-height: 115% font-family: " times="">Background and Aim:</span></b><span 12pt="" calibri="" en-us="" fa="" font-size:="" mso-ansi-language:="" mso-bidi-language:="" mso-fareast-font-family:="" mso-fareast-language:="" mso-fareast-theme-font:="" new="" style="line-height: 115% font-family: " times=""> The main purpose of periodontal treatment is to alleviate the clinical symptoms of inflammation. Photodynamic therapy which consists of light source and photosensitizer is believed to be influential as an adjunct to the conventional treatment in periodontitis. </span><span 12pt="" en-us="" font-size:="" mso-ansi-language:="" mso-bidi-language:="" mso-fareast-font-family:="" mso-fareast-language:="" new="" style="line-height: 115% font-family: " times="">The aim of this study was to clinically compare</span><span 12pt="" calibri="" en-us="" fa="" font-size:="" mso-ansi-language:="" mso-bidi-language:="" mso-fareast-font-family:="" mso-fareast-language:="" mso-fareast-theme-font:="" new="" style="line-height: 115% font-family: " times=""> the effect of using a single episode of photodynamic therapy as an adjunct treatment to scaling versus scaling per se within a three-month period in patients with chronic periodontitis in Isfahan.</span></p> <p><span 12pt="" calibri="" en-us="" fa="" font-size:="" mso-ansi-language:="" mso-bidi-language:="" mso-fareast-font-family:="" mso-fareast-language:="" mso-fareast-theme-font:="" new="" style="line-height: 115% font-family: " times=""><span 12pt="" calibri="" en-us="" font-size:="" mso-ansi-language:="" mso-bidi-language:="" mso-fareast-font-family:="" mso-fareast-language:="" new="" style="line-height: 115% font-family: " times=""><strong>Materials and Methods:</strong></span><span 12pt="" calibri="" en-us="" fa="" font-size:="" mso-ansi-language:="" mso-bidi-language:="" mso-fareast-font-family:="" mso-fareast-language:="" mso-fareast-theme-font:="" new="" style="line-height: 115% font-family: " times=""><span style="mso-spacerun: yes"><font face="Times New Roman" size="3">&nbsp;</font></span>This interventional </span><span 12pt="" en-us="" font-size:="" mso-ansi-language:="" mso-bidi-language:="" mso-fareast-font-family:="" mso-fareast-language:="" new="" style="line-height: 115% font-family: " times="">clinical trial was performed on 20 patients with mild to moderate chronic periodontitis, with pocket depth of 3-6mm and bleeding on probing in at least 3 teeth. Based on split-mouth design, each patient received scaling in one quadrant (as control group) and scaling accompanied by photodynamic therapy in the other one (as the case group). Clinical parameters including <a name="OLE_LINK22"></a><a name="OLE_LINK23"><span style="mso-bookmark: OLE_LINK22"><font face="Times New Roman" size="3">pocket depth, clinical attachment loss, bleeding on probing and </font></span></a>papillary bleeding index were measured initially and 90 days after treatment. </span><span 12pt="" calibri="" en-us="" font-size:="" mso-ansi-language:="" mso-bidi-language:="" mso-fareast-font-family:="" mso-fareast-language:="" new="" style="line-height: 115% font-family: " times="">The results were analyzed using Independent T-Test, Paired T-Test, Mann-Whitney and Wilcoxon Tests</span></span></p> <p></p> <p></p> <p><span 12pt="" calibri="" en-us="" fa="" font-size:="" mso-ansi-language:="" mso-bidi-language:="" mso-fareast-font-family:="" mso-fareast-language:="" mso-fareast-theme-font:="" new="" style="line-height: 115% font-family: " times=""><span 12pt="" calibri="" en-us="" font-size:="" mso-ansi-language:="" mso-bidi-language:="" mso-fareast-font-family:="" mso-fareast-language:="" new="" style="line-height: 115% font-family: " times="">&nbsp;</span></span></p> <p style="margin: 0cm 0cm 0pt text-align: justify line-height: 150% unicode-bidi: embed direction: ltr -ms-text-autospace: mso-layout-grid-align: none"><span 12pt="" calibri="" en-us="" fa="" font-size:="" mso-ansi-language:="" mso-bidi-language:="" mso-fareast-font-family:="" mso-fareast-language:="" mso-fareast-theme-font:="" new="" style="line-height: 115% font-family: " times=""><span 12pt="" calibri="" en-us="" font-size:="" mso-ansi-language:="" mso-bidi-language:="" mso-fareast-font-family:="" mso-fareast-language:="" new="" style="line-height: 115% font-family: " times=""><b><span 12pt="" font-size:="" mso-fareast-font-family:="" new="" style="line-height: 150% font-family: " times="">Results:</span></b><span font-size:="" new="" style="line-height: 150% font-family: " times=""> Bleeding indices decreased significantly</span><span 12pt="" font-size:="" mso-fareast-font-family:="" new="" style="line-height: 150% font-family: " times="">, with a significant difference between two groups. (p<0.001) Although,</span><span font-size:="" new="" style="line-height: 150% font-family: " times=""> the difference of reduction in pocket depth and clinical attachment loss was not significant between two groups (p= 0.61 and p= 0.14 respectively), decrease in these parameters after treatment was significant in each group (P<0.001). </span></span></span></p> <p><span 12pt="" calibri="" en-us="" fa="" font-size:="" mso-ansi-language:="" mso-bidi-language:="" mso-fareast-font-family:="" mso-fareast-language:="" mso-fareast-theme-font:="" new="" style="line-height: 115% font-family: " times=""><span 12pt="" calibri="" en-us="" font-size:="" mso-ansi-language:="" mso-bidi-language:="" mso-fareast-font-family:="" mso-fareast-language:="" new="" style="line-height: 115% font-family: " times="">&nbsp;</span></span></p> <p style="margin: 0cm 0cm 0pt text-align: left line-height: 150% unicode-bidi: embed direction: ltr"><span 12pt="" calibri="" en-us="" fa="" font-size:="" mso-ansi-language:="" mso-bidi-language:="" mso-fareast-font-family:="" mso-fareast-language:="" mso-fareast-theme-font:="" new="" style="line-height: 115% font-family: " times=""><span 12pt="" calibri="" en-us="" font-size:="" mso-ansi-language:="" mso-bidi-language:="" mso-fareast-font-family:="" mso-fareast-language:="" new="" style="line-height: 115% font-family: " times=""><b><span 12pt="" font-size:="" mso-fareast-font-family:="" new="" style="line-height: 150% font-family: " times="">Conclusion:</span></b><span font-size:="" new="" style="line-height: 150% font-family: " times=""> Using a single episode of photodynamic therapy was beneficial for reducing bleeding indices but it did not have extra clinical effects when compared with scaling per se.</span></span></span></p> <p><span 12pt="" calibri="" en-us="" fa="" font-size:="" mso-ansi-language:="" mso-bidi-language:="" mso-fareast-font-family:="" mso-fareast-language:="" mso-fareast-theme-font:="" new="" style="line-height: 115% font-family: " times=""><span 12pt="" calibri="" en-us="" font-size:="" mso-ansi-language:="" mso-bidi-language:="" mso-fareast-font-family:="" mso-fareast-language:="" new="" style="line-height: 115% font-family: " times="">&nbsp;</span></span></p> <p></p> <p></p> درمان فوتودینامیک,ماده ی حساس به نور,دیود ساطع کننده ی نور Photodynamic therapy, Chronic periodontitis, Scaling, Root 116 122 http://jrds.ir/browse.php?a_code=A-10-880-1&slc_lang=fa&sid=1 Sh Amini شیرین امینی sh.amini@khuisf.ac.ir 10031947532846009623 10031947532846009623 Yes Dentist Dentist Sh Shirani شیوا شیرانی 10031947532846009624 10031947532846009624 No Dentist دندانپزشDentist A Tahmourespour آرزو طهمورث پور 10031947532846009625 10031947532846009625 No Assistant Professor of Microbiology, Dept .of Basic Medical Sciences, Isfahan Azad University (Khorasgan Branch), Isfahan, Iran Assistant Professor of Microbiology, Dept .of Basic Medical Sciences, Isfahan Azad University (Khorasgan Branch), Isfahan, Iran