journal of research in dental sciences
مجله تحقیق در علوم دندانپزشکی
J Res Dent Sci
Medical Sciences
http://jrds.ir
1
admin
2008-4676
2228-7353
8
10.61186/jrds
14
13
fa
jalali
1393
10
1
gregorian
2015
1
1
11
4
online
1
fulltext
fa
مقایسه میزان سطح بزاقی و مایع شیار لثه ای آلکالین فسفاتاز دربیماران پریودنتیت سیگاری، غیرسیگاری و افراد سالم
The comparison of GCF and Salivary level of ALP in smokers, non-smokers with periodontitis and in healthy subjects
مواد دندانی
Dental materiall
مطالعه اصیل
original article
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<h5 dir="rtl" style="margin: 0cm 0cm 0pt text-align: justify line-height: 115% unicode-bidi: embed direction: rtl -ms-text-justify: kashida text-kashida: 0%"><b><span :="" b="" dir="rtl" face="Times New Roman" font="" h5="" lang="AR-SA" mso-ascii-font-family:="" mso-hansi-font-family:="" new="" roman="" size="3" span="" style="font-family: " times="">سابقه و هدف:<span style="mso-spacerun: yes"><font face="B Nazanin"> </font></span></span></b><span b="" color="#0000ff" dir="ltr" face="Times New Roman" font="" lang="AR-SA" mso-ascii-font-family:="" mso-bidi-font-family:="" mso-hansi-font-family:="" new="" roman="" size="3" span="" style="font-family: " times="">در بزاق و پریودنتیت در مطالعات محدودی مورد مطالعه قرار گرفته است و در هیچ تحقیقی ارتباط میزان غلظت</span><span b="" dir="ltr" lang="AR-SA" mso-bidi-font-family:="" new="" roman="" style="font-family: " times=""> </span><span dir="ltr" lang="X-NONE" style="font-size: 11pt mso-fareast-font-family: Calibri"><u><font color="#0000ff" face="Times New Roman">ALP</font></u></span><span b="" dir="ltr" lang="X-NONE" mso-bidi-font-family:="" new="" roman="" style="font-family: " times=""><font size="3"> </font></span><span .="" b="" color="#0000ff" dir="ltr" face="Times New Roman" font="" lang="AR-SA" mso-ascii-font-family:="" mso-bidi-font-family:="" mso-hansi-font-family:="" new="" roman="" size="3" span="" style="font-family: " times=""><font size="3">مایع شیار لثه­ای<span style="mso-spacerun: yes"><font face="B Nazanin"> </font></span></font><font size="3">و بزاق در بیماران پریودونتیت سیگاری، غیر سیگاری و افراد سالم بود</font></span><span b="" dir="ltr" lang="X-NONE" mso-bidi-font-family:="" new="" roman="" style="font-family: " times=""><font size="3">.</font></span></h5>
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<h5 dir="rtl" style="margin: 0cm 0cm 0pt text-align: justify unicode-bidi: embed direction: rtl"><span .="" 3="" 5="" 50-35="" 7-5="" 90="" :="" b="" color="#0000ff" dir="ltr" face="Times New Roman" font="" lang="AR-SA" mso-ascii-font-family:="" mso-bidi-font-family:="" mso-hansi-font-family:="" new="" roman="" size="3" span="" style="font-family: " times=""><font size="3">در مایع شیار لثه ای<span style="mso-spacerun: yes"><font face="B Nazanin"> </font></span></font><font size="3">و بزاق در نمونه های جمع آوری شده اندازه گیری شد. ازآزمون های آماری</font></span><font size="3"><span b="" dir="ltr" lang="AR-SA" mso-bidi-font-family:="" new="" roman="" style="font-family: " times=""> </span></font><font face="Times New Roman"><span dir="ltr" lang="X-NONE" style="font-size: 11pt mso-fareast-font-family: Calibri"><u><font color="#0000ff">ANOVA</font></u></span><span b="" dir="ltr" lang="X-NONE" style="mso-bidi-font-family: "><span style="mso-spacerun: yes"><font size="3"> </font></span></span></font><font size="3"><span b="" dir="rtl" face="Times New Roman" font="" h5="" lang="AR-SA" mso-ascii-font-family:="" mso-bidi-font-family:="" mso-hansi-font-family:="" new="" roman="" size="3" span="" style="font-family: " times="">یافته ها: میانگین میزان غلظت</span><span b="" dir="ltr" lang="AR-SA" mso-bidi-font-family:="" new="" roman="" style="font-family: " times=""> </span></font><span dir="ltr" lang="X-NONE" style="font-size: 11pt mso-fareast-font-family: Calibri"><u><font color="#0000ff" face="Times New Roman">ALP</font></u></span><span b="" dir="ltr" lang="X-NONE" mso-bidi-font-family:="" new="" roman="" style="font-family: " times=""><font size="3"> </font></span><span 0="</span" arial="" b="" dir="ltr" face="Times New Roman" font="" h5="" lang="AR-SA" mso-ascii-font-family:="" mso-bidi-font-family:="" mso-hansi-font-family:="" new="" roman="" size="3" span="" style="font-family: " times="">میانگین میزان غلظت</span><span b="" dir="ltr" lang="AR-SA" mso-bidi-font-family:="" new="" roman="" style="font-family: " times=""> </span><span dir="ltr" lang="X-NONE" style="font-size: 11pt mso-fareast-font-family: Calibri"><u><font color="#0000ff" face="Times New Roman">ALP</font></u></span><span b="" dir="ltr" lang="X-NONE" mso-bidi-font-family:="" new="" roman="" style="font-family: " times=""><font size="3"> </font></span><span 0="</span" arial="" b="" dir="ltr" face="Times New Roman" font="" lang="AR-SA" mso-ascii-font-family:="" mso-bidi-font-family:="" mso-hansi-font-family:="" new="" roman="" size="3" span="" style="font-family: " times="">میانگین میزان غلظت</span><span b="" dir="ltr" lang="AR-SA" mso-bidi-font-family:="" new="" roman="" style="font-family: " times=""> </span><font face="Times New Roman"><span dir="ltr" lang="X-NONE" style="font-size: 11pt mso-fareast-font-family: Calibri"><u><font color="#0000ff">ALP</font></u></span><span b="" dir="ltr" lang="X-NONE" style="mso-bidi-font-family: "><span style="mso-spacerun: yes"><font size="3"> </font></span></span></font><font size="3"><span arial="" b="" dir="rtl" face="Times New Roman" font="" h5="" lang="AR-SA" mso-ascii-font-family:="" mso-bidi-font-family:="" mso-hansi-font-family:="" new="" roman="" size="3" span="" style="font-family: " times=""><font size="3">نتیجه گیری: نتایج این تحقیق بیانگر آن است که میزان غلظت<span style="mso-spacerun: yes"><font face="B Nazanin"> </font></span></font><font size="3">مایع شیار لثه ای</font></span><font size="3"><span b="" dir="ltr" lang="AR-SA" mso-bidi-font-family:="" new="" roman="" style="font-family: " times=""> </span></font><span dir="ltr" lang="X-NONE" style="font-size: 11pt mso-fareast-font-family: Calibri"><u><font color="#0000ff" face="Times New Roman">ALP</font></u></span><span b="" dir="ltr" lang="X-NONE" mso-bidi-font-family:="" new="" roman="" style="font-family: " times=""><font size="3"> </font></span><span b="" color="#0000ff" dir="ltr" face="Times New Roman" font="" lang="AR-SA" mso-ascii-font-family:="" mso-bidi-font-family:="" mso-hansi-font-family:="" new="" roman="" size="3" span="" style="font-family: " times=""><font size="3">مایع شیار لثه ای در بیماران پریودنتیت سیگاری<span style="mso-spacerun: yes"><font face="B Nazanin"> </font></span></font><font size="3">بیشتر از افراد غیر سیگاری است. این امر شاید یکی از دلایلی است که در افراد سیگاری احتمال تخریب استخوان آلوئو لار بیشتر است.</font></span></font></h5>
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<h5 dir="rtl" style="margin: 0cm 0cm 0pt text-align: justify unicode-bidi: embed direction: rtl"><font size="3"><span lang="AR-SA" style="font-family: " b="" nazanin"="" mso-ascii-font-family:="" "times="" new="" roman="" bold"="" mso-hansi-font-family:="" bold""=""><font size="3"> </font></font></h5>
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<p style="margin: 0cm 0cm 0pt text-align: justify line-height: normal mso-pagination: none mso-outline-level: 1"><b><span font-size:="" new="" style="font-family: " times="">Abstract:</span></b></p>
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<p style="margin: 0cm 0cm 0pt text-align: justify line-height: normal mso-pagination: none tab-stops: 73.7pt"><b><span 10pt="" font-size:="" mso-bidi-language:="" new="" style="font-family: " times=""> </span></b></p>
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<p style="margin: 0cm 0cm 0pt text-align: justify"><b><span 10pt="" ar-ye="" font-size:="" mso-bidi-language:="" mso-fareast-font-family:="" new="" style="color: black line-height: 115% font-family: " times="">Background and Aim:</span></b><span 10pt="" ar-ye="" font-size:="" mso-bidi-language:="" mso-fareast-font-family:="" new="" style="color: black line-height: 115% font-family: " times=""> Periodontal destruction occurs in an episodic fashion, with periods of exacerbation and quiescence. It is therefore important to diagnose periodontal diseases in active phase. Various diagnostic markers have been identified in GCF and saliva. The aim of this study was to compare the salivary and GCF levels of alkaline phosphatase (ALP) in patients with periodontitis, smokers with periodontitis and healthy subjects. </span></p>
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<p style="margin: 0cm 0cm 0pt text-align: justify"><span 10pt="" ar-ye="" font-size:="" mso-bidi-language:="" mso-fareast-font-family:="" new="" style="color: black line-height: 115% font-family: " times=""> </span></p>
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<p style="margin: 0cm 0cm 0pt text-align: justify"><b><span 10pt="" ar-ye="" font-size:="" mso-bidi-language:="" mso-fareast-font-family:="" new="" style="color: black line-height: 115% font-family: " times="">Materials and Methods</span></b><span 10pt="" ar-ye="" font-size:="" mso-bidi-language:="" mso-fareast-font-family:="" new="" style="color: black line-height: 115% font-family: " times="">:In this descriptive study 90 subjects aged 30-50 without any apparent systemic disease were chosen and divided to 3 equal groups: smokers with periodontitis, non-smokers with periodontitis and healthy subjects. In healthy subjects, GCF samples were collected from gingival sulcus.<span style="mso-spacerun: yes"><font face="Times New Roman" size="2"> </font></span>In patients with periodontitis, GCF was collected from pockets of 5-7 mm of depth. About 5 ml of un-stimulated whole saliva was collected from all subjects. All GCF and salivary samples were sent to the laboratory for ALP measurement. ANOVA and Tukey's tests were used for statistical analysis.</span></p>
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<p style="margin: 0cm 0cm 0pt text-align: justify"><span 10pt="" ar-ye="" font-size:="" mso-bidi-language:="" mso-fareast-font-family:="" new="" style="color: black line-height: 115% font-family: " times=""> </span></p>
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<p style="margin: 0cm 0cm 0pt text-align: justify"><b><span 10pt="" ar-ye="" font-size:="" mso-bidi-language:="" mso-fareast-font-family:="" new="" style="color: black line-height: 115% font-family: " times="">Results:</span></b><span 10pt="" ar-ye="" font-size:="" mso-bidi-language:="" mso-fareast-font-family:="" new="" style="color: black line-height: 115% font-family: " times=""> The results of this study showed that the mean level of ALP in saliva and GCF was higher in the first and second groups compared to the third group. The mean level of ALP in GCF was higher in the first group compared to the second group. The mean level of ALP in saliva was not statistically different between the first and second group.</span></p>
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<p style="margin: 0cm 0cm 0pt text-align: justify"><span 10pt="" ar-ye="" font-size:="" mso-bidi-language:="" mso-fareast-font-family:="" new="" style="color: black line-height: 115% font-family: " times=""> </span></p>
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<p style="margin: 0cm 0cm 0pt text-align: justify"><b><span 10pt="" ar-ye="" font-size:="" mso-bidi-language:="" mso-fareast-font-family:="" new="" style="color: black line-height: 115% font-family: " times="">Conclusion:</span></b><span 10pt="" ar-ye="" font-size:="" mso-bidi-language:="" mso-fareast-font-family:="" new="" style="color: black line-height: 115% font-family: " times=""> It is possible to use both GCF and salivary levels of ALP as diagnostic markers for periodontitis. Higher levels of ALP in GCF samples of smokers with periodontitis could explain the higher rate of alveolar bone destruction in smokers.</span></p>
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آلکالین فسفاتاز, پریودنتیت, بزاق, مایع شیار لثه ای, استعمال دخانیات
Alkaline Phosphatase, Periodontitis, saliva, gingival crevicular fluid, smoking
236
241
http://jrds.ir/browse.php?a_code=A-10-12-1&slc_lang=fa&sid=1
M
Ketabi
محمد
کتابی
ketabimohammad@yahoo.com
10031947532846009603
10031947532846009603
Yes
M
Mesripour
منوچهر
مصری پور
10031947532846009604
10031947532846009604
No
E
Rafiei
احسان
رفیعی
10031947532846009605
10031947532846009605
No