<?xml version="1.0" encoding="utf-8"?>
<journal>
<title>journal of research in dental sciences</title>
<title_fa>مجله تحقیق در علوم دندانپزشکی</title_fa>
<short_title>J Res Dent Sci</short_title>
<subject>Medical Sciences</subject>
<web_url>http://jrds.ir</web_url>
<journal_hbi_system_id>1</journal_hbi_system_id>
<journal_hbi_system_user>admin</journal_hbi_system_user>
<journal_id_issn>2008-4676</journal_id_issn>
<journal_id_issn_online>2228-7353</journal_id_issn_online>
<journal_id_pii>8</journal_id_pii>
<journal_id_doi>10.66224/jrds</journal_id_doi>
<journal_id_iranmedex></journal_id_iranmedex>
<journal_id_magiran></journal_id_magiran>
<journal_id_sid>14</journal_id_sid>
<journal_id_nlai></journal_id_nlai>
<journal_id_science>13</journal_id_science>
<language>fa</language>
<pubdate>
	<type>jalali</type>
	<year>1401</year>
	<month>9</month>
	<day>1</day>
</pubdate>
<pubdate>
	<type>gregorian</type>
	<year>2022</year>
	<month>12</month>
	<day>1</day>
</pubdate>
<volume>19</volume>
<number>4</number>
<publish_type>online</publish_type>
<publish_edition>1</publish_edition>
<article_type>fulltext</article_type>
<articleset>
	<article>


	<language>fa</language>
	<article_id_doi></article_id_doi>
	<title_fa>مروری بر استفاده از بزاق برای تشخیص کووید19</title_fa>
	<title>Saliva As a Diagnostic Tool in Covid 19 Detection, A Review</title>
	<subject_fa>بیماری دهان</subject_fa>
	<subject>Oral Medicine</subject>
	<content_type_fa>مروری</content_type_fa>
	<content_type>Review article</content_type>
	<abstract_fa>&lt;h5 dir=&quot;RTL&quot; style=&quot;text-align:justify&quot;&gt;&lt;span style=&quot;font-size:12pt&quot;&gt;&lt;span style=&quot;direction:rtl&quot;&gt;&lt;span style=&quot;unicode-bidi:embed&quot;&gt;&lt;span new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;&lt;span style=&quot;font-weight:normal&quot;&gt;&lt;b&gt;&lt;span b=&quot;&quot; lang=&quot;AR-SA&quot; nazanin=&quot;&quot; style=&quot;font-family:&quot;&gt;&lt;span style=&quot;color:black&quot;&gt;سابقه و هدف&lt;/span&gt;&lt;/span&gt;&lt;/b&gt;&lt;span b=&quot;&quot; lang=&quot;AR-SA&quot; nazanin=&quot;&quot; style=&quot;font-family:&quot;&gt;&lt;span style=&quot;color:black&quot;&gt;: &lt;/span&gt;&lt;/span&gt;&lt;span lang=&quot;AR-SA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span b=&quot;&quot; nazanin=&quot;&quot; style=&quot;font-family:&quot;&gt;&lt;span style=&quot;color:black&quot;&gt;تاخیر در تشخیص&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span dir=&quot;LTR&quot; lang=&quot;X-NONE&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span bold=&quot;&quot; new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;&lt;span style=&quot;color:black&quot;&gt; SARS-CoV-2&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span lang=&quot;AR-SA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span b=&quot;&quot; nazanin=&quot;&quot; style=&quot;font-family:&quot;&gt;&lt;span style=&quot;color:black&quot;&gt;، مانع بزرگی در مهار اپیدمی فعلی کویید 19 میباشد. آزمایشات گسترده، عملی ترین راه برای خروج از بحران کنونی است. استاندارد طلایی فعلی برای تشخیص&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span dir=&quot;LTR&quot; lang=&quot;X-NONE&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span bold=&quot;&quot; new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;&lt;span style=&quot;color:black&quot;&gt; COVID-19&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span lang=&quot;AR-SA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span b=&quot;&quot; nazanin=&quot;&quot; style=&quot;font-family:&quot;&gt;&lt;span style=&quot;color:black&quot;&gt;، واکنش زنجیره ای پلیمراز رونویسی معکوس&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span dir=&quot;LTR&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span calibri=&quot;&quot; style=&quot;font-family:&quot;&gt;&lt;span style=&quot;color:black&quot;&gt;(&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span dir=&quot;LTR&quot; lang=&quot;X-NONE&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span bold=&quot;&quot; new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;&lt;span style=&quot;color:black&quot;&gt; RT-PCR) &lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span lang=&quot;AR-SA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span b=&quot;&quot; nazanin=&quot;&quot; style=&quot;font-family:&quot;&gt;&lt;span style=&quot;color:black&quot;&gt;با استفاده از سواب نازوفارنکس است. با این حال، جمع آوری سواب های نازوفارنکس به دلیل تهاجمی بودن، باعث ناراحتی بیماران و محدودیت انجام آزمایشهای مجدد می شود و این روش خطرات قابل توجهی را برای کارکنان مراقبت های بهداشتی به همراه دارد. بنابراین، ایجاد روشهای سریع و راحت برای تشخیص&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span dir=&quot;LTR&quot; lang=&quot;X-NONE&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span bold=&quot;&quot; new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;&lt;span style=&quot;color:black&quot;&gt; COVID-19 &lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span lang=&quot;AR-SA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span b=&quot;&quot; nazanin=&quot;&quot; style=&quot;font-family:&quot;&gt;&lt;span style=&quot;color:black&quot;&gt;ظرفیت آزمایشات را تا حد زیادی افزایش می دهد. از طرفی، بزاق یک کاندید امیدوار کننده برای تشخیص&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span dir=&quot;LTR&quot; lang=&quot;X-NONE&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span bold=&quot;&quot; new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;&lt;span style=&quot;color:black&quot;&gt; SARS-CoV-2 &lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span lang=&quot;AR-SA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span b=&quot;&quot; nazanin=&quot;&quot; style=&quot;font-family:&quot;&gt;&lt;span style=&quot;color:black&quot;&gt;است. هدف از این مرور، ارائه یک به روز رسانی و بررسی آخرین تحقیقات انجام شده و مقایسه روش ها و تکنیک های مختلف توسعه یافته برای تشخیص&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span dir=&quot;LTR&quot; lang=&quot;X-NONE&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span bold=&quot;&quot; new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;&lt;span style=&quot;color:black&quot;&gt; COVID-19 &lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span lang=&quot;AR-SA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span b=&quot;&quot; nazanin=&quot;&quot; style=&quot;font-family:&quot;&gt;&lt;span style=&quot;color:black&quot;&gt;به وسیله بزاق است&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span dir=&quot;LTR&quot; lang=&quot;X-NONE&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span bold=&quot;&quot; new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;&lt;span style=&quot;color:black&quot;&gt;.&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span lang=&quot;AR-SA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span b=&quot;&quot; nazanin=&quot;&quot; style=&quot;font-family:&quot;&gt;&lt;span style=&quot;color:black&quot;&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/h5&gt;

&lt;h5 dir=&quot;RTL&quot; style=&quot;text-align:justify&quot;&gt;&lt;span style=&quot;font-size:12pt&quot;&gt;&lt;span style=&quot;direction:rtl&quot;&gt;&lt;span style=&quot;unicode-bidi:embed&quot;&gt;&lt;span new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;&lt;span style=&quot;font-weight:normal&quot;&gt;&lt;b&gt;&lt;span b=&quot;&quot; lang=&quot;AR-SA&quot; nazanin=&quot;&quot; style=&quot;font-family:&quot;&gt;&lt;span style=&quot;color:black&quot;&gt;مواد و روش&#8204;ها:&lt;/span&gt;&lt;/span&gt;&lt;/b&gt; &lt;span lang=&quot;AR-SA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span b=&quot;&quot; nazanin=&quot;&quot; style=&quot;font-family:&quot;&gt;&lt;span style=&quot;color:black&quot;&gt;در این مقاله مروری، جمع آوری اطلاعات از طریق جستجوی مقالات موجود در ژورنال های داخلی و خارجی، با استفاده از پایگاه های اطلاعاتی چون&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span dir=&quot;LTR&quot; lang=&quot;X-NONE&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span bold=&quot;&quot; new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;&lt;span style=&quot;color:black&quot;&gt;: PubMed&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span lang=&quot;AR-SA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span b=&quot;&quot; nazanin=&quot;&quot; style=&quot;font-family:&quot;&gt;&lt;span style=&quot;color:black&quot;&gt;،&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span dir=&quot;LTR&quot; lang=&quot;X-NONE&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span bold=&quot;&quot; new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;&lt;span style=&quot;color:black&quot;&gt;PubMed Central &lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span lang=&quot;AR-SA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span b=&quot;&quot; nazanin=&quot;&quot; style=&quot;font-family:&quot;&gt;&lt;span style=&quot;color:black&quot;&gt;،&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span dir=&quot;LTR&quot; lang=&quot;X-NONE&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span bold=&quot;&quot; new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;&lt;span style=&quot;color:black&quot;&gt;Medline &lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span lang=&quot;AR-SA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span b=&quot;&quot; nazanin=&quot;&quot; style=&quot;font-family:&quot;&gt;&lt;span style=&quot;color:black&quot;&gt;،&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span dir=&quot;LTR&quot; lang=&quot;X-NONE&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span bold=&quot;&quot; new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;&lt;span style=&quot;color:black&quot;&gt;EBSCO &lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span lang=&quot;AR-SA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span b=&quot;&quot; nazanin=&quot;&quot; style=&quot;font-family:&quot;&gt;&lt;span style=&quot;color:black&quot;&gt;، &lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span dir=&quot;LTR&quot; lang=&quot;X-NONE&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span bold=&quot;&quot; new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;&lt;span style=&quot;color:black&quot;&gt;Google Scholar &lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span lang=&quot;AR-SA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span b=&quot;&quot; nazanin=&quot;&quot; style=&quot;font-family:&quot;&gt;&lt;span style=&quot;color:black&quot;&gt;و&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span dir=&quot;LTR&quot; lang=&quot;X-NONE&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span bold=&quot;&quot; new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;&lt;span style=&quot;color:black&quot;&gt; Embase &lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span lang=&quot;AR-SA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span b=&quot;&quot; nazanin=&quot;&quot; style=&quot;font-family:&quot;&gt;&lt;span style=&quot;color:black&quot;&gt;با واژه های&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span dir=&quot;LTR&quot; lang=&quot;X-NONE&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span bold=&quot;&quot; new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;&lt;span style=&quot;color:black&quot;&gt;Saliva &lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span lang=&quot;AR-SA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span b=&quot;&quot; nazanin=&quot;&quot; style=&quot;font-family:&quot;&gt;&lt;span style=&quot;color:black&quot;&gt;،&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span dir=&quot;LTR&quot; lang=&quot;X-NONE&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span bold=&quot;&quot; new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;&lt;span style=&quot;color:black&quot;&gt;Covid_19&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span lang=&quot;AR-SA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span b=&quot;&quot; nazanin=&quot;&quot; style=&quot;font-family:&quot;&gt;&lt;span style=&quot;color:black&quot;&gt; ،&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span dir=&quot;LTR&quot; lang=&quot;X-NONE&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span bold=&quot;&quot; new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;&lt;span style=&quot;color:black&quot;&gt;Covid_19 Test &lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span lang=&quot;AR-SA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span b=&quot;&quot; nazanin=&quot;&quot; style=&quot;font-family:&quot;&gt;&lt;span style=&quot;color:black&quot;&gt;،&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span dir=&quot;LTR&quot; lang=&quot;X-NONE&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span bold=&quot;&quot; new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;&lt;span style=&quot;color:black&quot;&gt;Salivary Test&amp;nbsp; &lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span lang=&quot;AR-SA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span b=&quot;&quot; nazanin=&quot;&quot; style=&quot;font-family:&quot;&gt;&lt;span style=&quot;color:black&quot;&gt;در فاصله بین سالهای 2019 تا 2021 صورت گرفت. در بین مراجع مرتبط، تعداد47&amp;nbsp; مقاله معتبر که بارها مورد استناد قرار گرفته بودند و به روزتر بودند، انتخاب گردیدند&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span dir=&quot;LTR&quot; lang=&quot;X-NONE&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span bold=&quot;&quot; new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;&lt;span style=&quot;color:black&quot;&gt;.&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span lang=&quot;AR-SA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span b=&quot;&quot; nazanin=&quot;&quot; style=&quot;font-family:&quot;&gt;&lt;span style=&quot;color:black&quot;&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/h5&gt;

&lt;h5 dir=&quot;RTL&quot; style=&quot;text-align:justify&quot;&gt;&lt;span style=&quot;font-size:12pt&quot;&gt;&lt;span style=&quot;direction:rtl&quot;&gt;&lt;span style=&quot;unicode-bidi:embed&quot;&gt;&lt;span new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;&lt;span style=&quot;font-weight:normal&quot;&gt;&lt;b&gt;&lt;span b=&quot;&quot; lang=&quot;AR-SA&quot; nazanin=&quot;&quot; style=&quot;font-family:&quot;&gt;&lt;span style=&quot;color:black&quot;&gt;نتیجه&#8204;گیری&lt;/span&gt;&lt;/span&gt;&lt;/b&gt;&lt;span b=&quot;&quot; lang=&quot;AR-SA&quot; nazanin=&quot;&quot; style=&quot;font-family:&quot;&gt;&lt;span style=&quot;color:black&quot;&gt;: &lt;/span&gt;&lt;/span&gt;&lt;span lang=&quot;AR-SA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span b=&quot;&quot; nazanin=&quot;&quot; style=&quot;font-family:&quot;&gt;&lt;span style=&quot;color:black&quot;&gt;به نظر می رسد بزاق یک منبع جایگزین قابل قبول برای تشخیص&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span dir=&quot;LTR&quot; lang=&quot;X-NONE&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span bold=&quot;&quot; new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;&lt;span style=&quot;color:black&quot;&gt; SARS-CoV-2 &lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span lang=&quot;AR-SA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span b=&quot;&quot; nazanin=&quot;&quot; style=&quot;font-family:&quot;&gt;&lt;span style=&quot;color:black&quot;&gt;است. همچنین، &lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span lang=&quot;FA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span b=&quot;&quot; nazanin=&quot;&quot; style=&quot;font-family:&quot;&gt;&lt;span style=&quot;color:black&quot;&gt;افزایش تقاضا &lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span lang=&quot;AR-SA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span b=&quot;&quot; nazanin=&quot;&quot; style=&quot;font-family:&quot;&gt;&lt;span style=&quot;color:black&quot;&gt;&amp;nbsp;برای بسترهای تشخیصی جدید کویید19، با نمونه های غیرتهاجمی و جمع آوری توسط خود فرد، می تواند پس از ایجاد یک برنامه استراتژیک، به خوبی طراحی شده و اجرا شود&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span dir=&quot;LTR&quot; lang=&quot;X-NONE&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span bold=&quot;&quot; new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;&lt;span style=&quot;color:black&quot;&gt;. &lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span lang=&quot;AR-SA&quot; style=&quot;font-size:11.0pt&quot;&gt;&lt;span b=&quot;&quot; nazanin=&quot;&quot; style=&quot;font-family:&quot;&gt;&lt;span style=&quot;color:black&quot;&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/h5&gt;

&lt;h5 dir=&quot;RTL&quot; style=&quot;text-align:justify&quot;&gt;&lt;br&gt;
&lt;span style=&quot;font-size:12pt&quot;&gt;&lt;span style=&quot;direction:rtl&quot;&gt;&lt;span style=&quot;unicode-bidi:embed&quot;&gt;&lt;span new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;&lt;span style=&quot;font-weight:normal&quot;&gt;&lt;span lang=&quot;X-NONE&quot; dir=&quot;LTR&quot; style=&quot;color:black&quot;&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/h5&gt;
&lt;span style=&quot;font-size:12pt&quot;&gt;&lt;span style=&quot;direction:rtl&quot;&gt;&lt;span style=&quot;unicode-bidi:embed&quot;&gt;&lt;span new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;&lt;span style=&quot;font-weight:normal&quot;&gt;&lt;span b=&quot;&quot; lang=&quot;AR-SA&quot; nazanin=&quot;&quot; style=&quot;font-family:&quot;&gt;&lt;span style=&quot;color:black&quot;&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;</abstract_fa>
	<abstract>&lt;span style=&quot;font-size:12pt&quot;&gt;&lt;span new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;&lt;b&gt;Background and Aim&lt;/b&gt;: &lt;span style=&quot;font-size:10.0pt&quot;&gt;Delayed detection of SARS-CoV-2 has been a major hindrance in curbing the current COVID-19 pandemic. Wide spread testing is the most practical way out of the current crisis. The current gold standard for COVID-19 diagnosis is real-time reverse transcription polymerase chain reaction (RT-PCR) detection of SARS-CoV-2 from nasopharyngeal swabs. However, collecting nasopharyngeal swabs causes discomfort to patients due to the procedure&amp;rsquo;s invasiveness, limiting compliance for repeat testing, and the procedure presents a considerable risk to healthcare workers. Therefore, developing rapid and convenient ways of testing for COVID-19 will greatly enhance the capacity of testing. Alternatively, saliva is a promising candidate for SARS-CoV-2 diagnostics. The purpose of this review is to provide an update and review of the composition of the latest research and to compare the various methods and techniques developed for the diagnosis of COVID-19 by saliva.&lt;/span&gt;&lt;span dir=&quot;RTL&quot; lang=&quot;FA&quot; style=&quot;font-size:10.0pt&quot;&gt;&lt;span style=&quot;font-family:&quot;B Nazanin&quot;&quot;&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;br&gt;
&lt;span style=&quot;font-size:12pt&quot;&gt;&lt;span new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;&lt;b&gt;Material and Methods:&lt;/b&gt;&lt;b&gt; &lt;/b&gt;&lt;span style=&quot;font-size:10.0pt&quot;&gt;In this review article, data were collected by searching articles which were published between year 2019 and 2021 in domestic and foreign journals, using databases such as: PubMed, PubMed Central, Medline, EBSCO, Google Scholar and Embase with keywords: Saliva, Covid_19, Covid_19 Test, Salivary Test. Among the relevant authorities, the articles that were cited many times and were more up to date, were selected.&lt;/span&gt;&lt;span dir=&quot;RTL&quot; lang=&quot;FA&quot; style=&quot;font-size:10.0pt&quot;&gt;&lt;span style=&quot;font-family:&quot;B Nazanin&quot;&quot;&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;br&gt;
&lt;span style=&quot;font-size:12pt&quot;&gt;&lt;span new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;&lt;b&gt;&lt;span style=&quot;color:black&quot;&gt;Conclusion&lt;/span&gt;&lt;/b&gt;&lt;b&gt;&lt;span style=&quot;font-size:10.0pt&quot;&gt;&lt;span style=&quot;color:black&quot;&gt;:&lt;/span&gt;&lt;/span&gt;&lt;/b&gt; &lt;span style=&quot;font-size:10.0pt&quot;&gt;that saliva is an acceptable alternative source for detecting SARS-CoV-2.&amp;nbsp; It imposes the development ofnew strategies for COVID-19 diagnosis; however, despite the colossal demand for novel diagnostic platforms with non-invasive and self-collection samples of COVID-19, the accuracy of salivary SARS-CoV-2 platforms are still not well- elucidated. &lt;/span&gt;&lt;span dir=&quot;RTL&quot; lang=&quot;FA&quot; style=&quot;font-size:10.0pt&quot;&gt;&lt;span style=&quot;font-family:&quot;B Nazanin&quot;&quot;&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;br&gt;
&lt;span style=&quot;font-size:12pt&quot;&gt;&lt;span new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;&lt;b&gt;Key words&lt;/b&gt;: &lt;span style=&quot;font-size:10.0pt&quot;&gt;Saliva, Covid_19, Covid_19 Test, Salivary Test &lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;br&gt;
&lt;span style=&quot;font-size:12pt&quot;&gt;&lt;span new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;&lt;b&gt;Background and Aim&lt;/b&gt;: &lt;span style=&quot;font-size:10.0pt&quot;&gt;Delayed detection of SARS-CoV-2 has been a major hindrance in curbing the current COVID-19 pandemic. Wide spread testing is the most practical way out of the current crisis. The current gold standard for COVID-19 diagnosis is real-time reverse transcription polymerase chain reaction (RT-PCR) detection of SARS-CoV-2 from nasopharyngeal swabs. However, collecting nasopharyngeal swabs causes discomfort to patients due to the procedure&amp;rsquo;s invasiveness, limiting compliance for repeat testing, and the procedure presents a considerable risk to healthcare workers. Therefore, developing rapid and convenient ways of testing for COVID-19 will greatly enhance the capacity of testing. Alternatively, saliva is a promising candidate for SARS-CoV-2 diagnostics. The purpose of this review is to provide an update and review of the composition of the latest research and to compare the various methods and techniques developed for the diagnosis of COVID-19 by saliva.&lt;/span&gt;&lt;span dir=&quot;RTL&quot; lang=&quot;FA&quot; style=&quot;font-size:10.0pt&quot;&gt;&lt;span style=&quot;font-family:&quot;B Nazanin&quot;&quot;&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;br&gt;
&lt;span style=&quot;font-size:12pt&quot;&gt;&lt;span new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;&lt;b&gt;Material and Methods:&lt;/b&gt;&lt;b&gt; &lt;/b&gt;&lt;span style=&quot;font-size:10.0pt&quot;&gt;In this review article, data were collected by searching articles which were published between year 2019 and 2021 in domestic and foreign journals, using databases such as: PubMed, PubMed Central, Medline, EBSCO, Google Scholar and Embase with keywords: Saliva, Covid_19, Covid_19 Test, Salivary Test. Among the relevant authorities, the articles that were cited many times and were more up to date, were selected.&lt;/span&gt;&lt;span dir=&quot;RTL&quot; lang=&quot;FA&quot; style=&quot;font-size:10.0pt&quot;&gt;&lt;span style=&quot;font-family:&quot;B Nazanin&quot;&quot;&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;br&gt;
&lt;span style=&quot;font-size:12pt&quot;&gt;&lt;span new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;&lt;b&gt;&lt;span style=&quot;color:black&quot;&gt;Conclusion&lt;/span&gt;&lt;/b&gt;&lt;b&gt;&lt;span style=&quot;font-size:10.0pt&quot;&gt;&lt;span style=&quot;color:black&quot;&gt;:&lt;/span&gt;&lt;/span&gt;&lt;/b&gt; &lt;span style=&quot;font-size:10.0pt&quot;&gt;that saliva is an acceptable alternative source for detecting SARS-CoV-2.&amp;nbsp; It imposes the development ofnew strategies for COVID-19 diagnosis; however, despite the colossal demand for novel diagnostic platforms with non-invasive and self-collection samples of COVID-19, the accuracy of salivary SARS-CoV-2 platforms are still not well- elucidated. &lt;/span&gt;&lt;span dir=&quot;RTL&quot; lang=&quot;FA&quot; style=&quot;font-size:10.0pt&quot;&gt;&lt;span style=&quot;font-family:&quot;B Nazanin&quot;&quot;&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;br&gt;
&amp;nbsp;</abstract>
	<keyword_fa>تست بزاقی , تست کوید 19, کوید 19 و بزاق</keyword_fa>
	<keyword>Saliva, Covid_19, Covid_19 Test, Salivary Test</keyword>
	<start_page>355</start_page>
	<end_page>368</end_page>
	<web_url>http://jrds.ir/browse.php?a_code=A-10-1525-3&amp;slc_lang=fa&amp;sid=1</web_url>


<author_list>
	<author>
	<first_name>Kimia</first_name>
	<middle_name></middle_name>
	<last_name>Ghods</last_name>
	<suffix></suffix>
	<first_name_fa>کیمیا</first_name_fa>
	<middle_name_fa></middle_name_fa>
	<last_name_fa>قدس</last_name_fa>
	<suffix_fa></suffix_fa>
	<email></email>
	<code>100319475328460019417</code>
	<orcid>100319475328460019417</orcid>
	<coreauthor>No</coreauthor>
	<affiliation></affiliation>
	<affiliation_fa>عضو مرکز تحقیقاتی مواد دندانی، دانشگاه علوم پزشکی آزاد اسلامی، تهران، ایران</affiliation_fa>
	 </author>


	<author>
	<first_name>Arezoo</first_name>
	<middle_name></middle_name>
	<last_name>Alaee</last_name>
	<suffix></suffix>
	<first_name_fa>آرزو</first_name_fa>
	<middle_name_fa></middle_name_fa>
	<last_name_fa>علایی</last_name_fa>
	<suffix_fa></suffix_fa>
	<email></email>
	<code>100319475328460019418</code>
	<orcid>100319475328460019418</orcid>
	<coreauthor>Yes
</coreauthor>
	<affiliation></affiliation>
	<affiliation_fa>گروه بیماری های دهان و فک و صورت، عضو مرکز تحقیقاتی مواد دندانی، دانشکده دندانپزشکی دانشگاه علوم پزشکی آزاد اسلامی، تهران، ایران</affiliation_fa>
	 </author>


	<author>
	<first_name>Sarina</first_name>
	<middle_name></middle_name>
	<last_name>Javid</last_name>
	<suffix></suffix>
	<first_name_fa>سارینا</first_name_fa>
	<middle_name_fa></middle_name_fa>
	<last_name_fa>جاوید</last_name_fa>
	<suffix_fa></suffix_fa>
	<email></email>
	<code>100319475328460019419</code>
	<orcid>100319475328460019419</orcid>
	<coreauthor>No</coreauthor>
	<affiliation></affiliation>
	<affiliation_fa>عضو مرکز تحقیقاتی مواد دندانی، دانشگاه علوم پزشکی آزاد اسلامی، تهران، ایران</affiliation_fa>
	 </author>


	<author>
	<first_name>Fatemeh</first_name>
	<middle_name></middle_name>
	<last_name>Jafari</last_name>
	<suffix></suffix>
	<first_name_fa>فاطمه</first_name_fa>
	<middle_name_fa></middle_name_fa>
	<last_name_fa>جعفری</last_name_fa>
	<suffix_fa></suffix_fa>
	<email></email>
	<code>100319475328460019420</code>
	<orcid>100319475328460019420</orcid>
	<coreauthor>No</coreauthor>
	<affiliation></affiliation>
	<affiliation_fa>عضو مرکز تحقیقاتی مواد دندانی، دانشگاه علوم پزشکی آزاد اسلامی، تهران، ایران</affiliation_fa>
	 </author>


</author_list>


	</article>
</articleset>
</journal>
