[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: Volume 14, Number 2 (J Res Dent Sci 2017) ::
J Res Dent Sci 2017, 14(2): 109-117 Back to browse issues page
Clinical effects of chlorhexidine gel in the treatment of chronic periodontitis
Dr F Taleghani, Dr R Sadeghi *, Eng N Valaei, Dr R Nejadi, Dr AM Nematollah
Assistant professorDept. of Periodontics, Dental School, Shahed University, Tehran,Iran , sadeghi@shahed.ac.ir
Abstract:   (826 Views)

Background and Aim

Local antibacterial agents containing chlorhexidine (CHX) are used as an adjunct to conventional treatment in periodontal patients. In this study, a sustained release, xanthan- based CHX gel was used for non surgical treatment in moderate to advanced periodontitis.

Methods and Materials

In this randomized controlled split-mouth clinical trial, 40 periodontal pockets with probing pocket depth > 5 mm were selected and randomly assigned to the case and control groups. Scaling and root planing (SRP) were performed thoroughly at all sites. Then, chlorhexidine gel and placebo gel were applied subgingivally in test and control sites, respectively. The gels’ application was done two times with one week interval. The clinical parameters including plaque index (PI), papillary bleeding index (PBI), pocket depth (PD) and clinical attachment level (CAL) were evaluated at baseline, after 1 and 3 months. Data analysis was performed using U Mann-Whitney and Friedman tests. 

Results

Statistically significant improvements were observed in PBI, CAL and PD parameters following treatment in each group after 1 and 3 months. Comparison between the two treatment groups showed no significant differences in clinical parameters at any time point.

Conclusion

According to the findings of this study, adjunctive subgingival application of chlorhexidine gel did not improve clinical parameters significantly compared to scaling and root planing treatment in moderate-to-severe chronic periodontitis.

Key words

Locally delivered drugs, Chronic periodontitis, Chlorhexidine,Treatment Outcome

Keywords: Locally delivered drugs, Chronic periodontitis, Chlorhexidine, Treatment Outcome
Full-Text [PDF 12 kb]   (189 Downloads)    
Type of Study: original article | Subject: Perio
Send email to the article author

Add your comments about this article
Your username or email:

Write the security code in the box >



XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Taleghani F, Sadeghi R, Valaei N, Nejadi R, Nematollah A. Clinical effects of chlorhexidine gel in the treatment of chronic periodontitis. J Res Dent Sci. 2017; 14 (2) :109-117
URL: http://jrds.ir/article-1-820-en.html
Volume 14, Number 2 (J Res Dent Sci 2017) Back to browse issues page
مجله تحقیق در علوم دندانپزشکی Res Dent Sci
Persian site map - English site map - Created in 0.049 seconds with 794 queries by yektaweb 3461