[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: Volume 14, Number 2 (J Res Dent Sci 2017) ::
J Res Dent Sci 2017, 14(2): 77-82 Back to browse issues page
Evaluation of Mucosamin Compound Concentration Effect on Optical Density and Proliferation of Human Fibroblast Cells
Dr M Jafaritehrani *, Dr B Houshmand, H Semyari, H Semyari
, jafarimorteza098@gmail.com
Abstract:   (1091 Views)

Background and Aim: Management of soft tissue scares is one of main concerns during dental practice. Base several studies are pointed to effect of topical compound on wound healing the main objective of this study were on to study the effect of Mucosamin compound on Growth and Proliferation of Human Fibroblast Cells in an in-vitro environment.

Material and Methods: In this experimental invitro study, human fibroblast cells were treated with 0.1% to 1% of Mucosamin compound for 48, 72 and 96 hours in three replication. Also on different 96 wells plated the effect of 1% to 15% of Mucosamin compound on human fibroblast cells in three replication were treated. Finally the optical concentration of fibroblast cell were recorded on 580nm using UV Spectrophotometer. Result were subjected to one way and two way Variance analysis using SPSS software. 

Results: Results showed of Mucosamin compound with essential substance of hyaluronic acid and amino acids at lower concentration than 1% have no significant effect on wound healing and growth of fibroblast cells. Also results showed prolonging the treatment up to 96 hours lead to increase in cells growth or optical density of fibroblast cells.

Conclusion: Results showed Mucosamin compound with higher concentration than 1% has toxic effect on fibroblast cells. Further study to confirmed effect of this compound on wound healing and growth of fibroblast cells using histological and clinical examination is required.

Keywords: Mucosamin Compound, Fibroblast cells, Wound Healing
Full-Text [PDF 12 kb]   (220 Downloads)    
Type of Study: original article | Subject: oral surgery
Send email to the article author

Add your comments about this article
Your username or email:

Write the security code in the box >



XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Jafaritehrani M, Houshmand B, Semyari H, Semyari H. Evaluation of Mucosamin Compound Concentration Effect on Optical Density and Proliferation of Human Fibroblast Cells. J Res Dent Sci. 2017; 14 (2) :77-82
URL: http://jrds.ir/article-1-812-en.html
Volume 14, Number 2 (J Res Dent Sci 2017) Back to browse issues page
مجله تحقیق در علوم دندانپزشکی Res Dent Sci
Persian site map - English site map - Created in 0.049 seconds with 797 queries by yektaweb 3506