Abstract:

  Background and Aim : Diabetes Mellitus (DM) is a complex metabolic disorder. The determination of saliva components in these patients may be useful in further understanding the oral finding in this condition. The aim of this study was to evaluate the salivary Alpha- Amylase level in type II diabetic patients.

  Materials and Methods : In this case- control study, 40 patients with type II DM and 40 healthy subjects were selected. All participants were matched for age and sex. Dental and oral status was assessed for all subjects. Whole unstimulated saliva samples were collected during 5 minute to determine salivary flow rate and amylase concentration. The data was analyzed using t-test.

  Results : Salivary alpha- amylase rate was significantly higher in patients with type II DM (106217.5±77661.24 Vs. 68257.5±29276.12IU/dl), (P= 0.05), Salivary flow rate was significantly lower in type II diabetic patients than control group ( 0.32±0.14 Vs. 0.39±0.17),(P=0.001). Dry mouth ,burning sensation and DMFT index were significantly higher in type II DM patients (P=0.003).

  Conclusion : Salivary alpha amylase level was significantly higher in type II diabetic patients