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Comparison the effect of Ferula gummosa and Chlorhexidine on dental cariogenic bacteria
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Bahareh Nazemi salman    , Ali Yazdi Nejad , Fakhri Haghi , Mahtab Mohammadi Gheydari , Samira Basir shabestari * |
| Iran University of Medical Sciences, Tehran, Iran , samira_bsh2@yahoo.com |
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Abstract: (1466 Views) |
Abstract
Background & Aim: Dental caries is the most widespread chronic disease ,in which bacterial plaque plays a major role in their occurrence. Considering the importance of dental plaque control, side effects of chemical products, availability of medicinal plants in the ecosystem of our country, therefore this study was conducted with the aim of comparing the effects of Ferula gummosa plant and chlorhexidine on cariogenic bacteria.
Material and Methods: In this laboratory study, the aerial parts of the plant were collected from Tarom/Zanjan region. Herbarium sample identification was done by Zanjan Faculty of Pharmacy.The essential oil of Ferula gummosa was obtained by Clevenger apparatus and prepared by distillation with water. Serial dilutions of essential oils were prepared and the minimum inhibitory concentration and the minimum lethal concentration were determined. Disk diffusion method was used to evaluate the antibacterial effects of essential oilon the tested bacteria (Streptococcus mutans, subrinus, salivarius and Lactobacillus acidophilus). In order to evaluate bacterial sensitivity to essential oil and chlorhexidine, well plate method was used. The dates were entered the computer by the SPSS 22 software aand analyzed by independent Ttest.
Results: In some samples, the antibacterial properties of Ferula gummosa were similar to chlorhexidine. Ferula gummosa plant extract had the most effect on Streptococcus subrinus and Salivarius. The diameter of the inhibitory zone in Streptococcus subrinus bacteria was non-significantly greater than that of chlorhexidine.
Conclusion: The antimicrobial effect of Ferula gummos essential oil on cariogenic bacteria was similar to chlorhexidine. It is recommended to use the compounds of this plant as an alternative to other chemical products (mouthwash and toothpaste).
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| Keywords: anti-infective agents, bacteria, plant extract, mouthwash |
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Full-Text [PDF 913 kb]
(874 Downloads)
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Type of Study: original article |
Subject:
Oral Medicine
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